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Q4KJD3 (Q4KJD3_PSEF5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401
Gene names
Name:msrA1 HAMAP MF_01401
Synonyms:msrA_2 EMBL AAY95915.1
Ordered Locus Names:PFL_0506
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site581 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q4KJD3 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: ED643FA5311CB471

FASTA21523,743
        10         20         30         40         50         60 
MVLRSEILVN KNVLPTKEQA LPGRETPMAL PAEHYVNGNP LLGPFPGNVD FAIFGLGCFW 

        70         80         90        100        110        120 
GAERRFWQRE GVFSTCVGYA GGFTPNPTYE EVCSGLTGHT EVVLVVYEPE KVSYKELLAM 

       130        140        150        160        170        180 
FWELHNPTQG MRQGNDIGTQ YRSVIYATNP TQLEQALHSR DVFQAELTKA GLGTITTEIE 

       190        200        210 
EAPTVYFAEA YHQQYLAKNP EGYCGIGGTG VTCPI 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000076 Genomic DNA. Translation: AAY95915.1.
RefSeqYP_257650.1. NC_004129.6.

3D structure databases

ProteinModelPortalQ4KJD3.
SMRQ4KJD3. Positions 16-214.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4KJD3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3481097.
GenomeReviewsGene locus PFL_0506 in contig CP000076_GR.
KEGGpfl:PFL_0506.
NMPDRfig|220664.3.peg.1990.
PATRIC19870165. VBIPseFlu72549_0521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMASAIYCTS.
PhylomeDBQ4KJD3.
ProtClustDBPRK00058.

Enzyme and pathway databases

BioCycPFLU220664:PFL_0506-MONOMER.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ4KJD3_PSEF5
AccessionPrimary (citable) accession number: Q4KJD3
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)