Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPPRO220664:G1G4K-670-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:PFL_0655
OrganismiPseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Taxonomic identifieri220664 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000008540 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002577721 – 365Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST365

Interactioni

Protein-protein interaction databases

STRINGi220664.PFL_0655

Structurei

3D structure databases

ProteinModelPortaliQ4KIY6
SMRiQ4KIY6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

Q4KIY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREETAEQPA PLRSGLTTGS CATATSLAAA RLLLEGSNAD AVQIILPKGK
60 70 80 90 100
QVQMRLEFCR HTADGAEAGT IKDAGDDPDV THGALLYSRV RLTPEPGIRF
110 120 130 140 150
IAGQGVGTVT RPGLVLAVGE PAINPIPRRM IGEHLQRLAE ERAYPGGFEV
160 170 180 190 200
TVNVEGGAEL ALKTMNPRLG ILGGLSILGT SGIVRPFSCA AYIASIHQGI
210 220 230 240 250
DVAKTNGYLH IAACTGNASE DTMRRVYELP EIALIEMGDF VGAVLKHLRK
260 270 280 290 300
VPVDKLSLCG GFGKISKLAA GHMDLHSRHS SIDLSQLAQW AADAGADPAL
310 320 330 340 350
QQAIRQANTS QQALAMASAA GVALGDAVCR HALDFARSVV PPQVQVEVFA
360
IDRQGGIVGH AGGFQ
Length:365
Mass (Da):38,238
Last modified:October 31, 2006 - v2
Checksum:iC02BFE639363F303
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA Translation: AAY96062.2
RefSeqiWP_011059023.1, NC_004129.6

Genome annotation databases

EnsemblBacteriaiAAY96062; AAY96062; PFL_0655
KEGGipfl:PFL_0655
PATRICifig|220664.5.peg.672

Similar proteinsi

Entry informationi

Entry nameiCBID_PSEF5
AccessioniPrimary (citable) accession number: Q4KIY6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: May 23, 2018
This is version 73 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health