ID   RLMF_PSEF5              Reviewed;         341 AA.
AC   Q4KHU0;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 2.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase F;
DE            EC=2.1.1.48;
DE   AltName: Full=23S rRNA mA1618 methyltransferase;
DE   AltName: Full=rRNA adenine N-6-methyltransferase;
GN   Name=rlmF; OrderedLocusNames=PFL_1062;
OS   Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=220664;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15980861; DOI=10.1038/nbt1110;
RA   Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.A.,
RA   Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA   Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A.,
RA   Rosovitz M.J., Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W.,
RA   Nelson W.C., Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A.,
RA   Pierson L.S. III, Thomashow L.S., Loper J.E.;
RT   "Complete genome sequence of the plant commensal Pseudomonas
RT   fluorescens Pf-5.";
RL   Nat. Biotechnol. 23:873-878(2005).
CC   -!- FUNCTION: Specifically methylates the adenine in position 1618 of
CC       23S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-
CC       homocysteine + rRNA containing N(6)-methyladenine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       METT10D/rlmF family.
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DR   EMBL; CP000076; AAY90349.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_258193.2; -.
DR   GeneID; 3477473; -.
DR   GenomeReviews; CP000076_GR; PFL_1062.
DR   KEGG; pfl:PFL_1062; -.
DR   NMPDR; fig|220664.3.peg.2506; -.
DR   HOGENOM; Q4KHU0; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008988; F:rRNA (adenine-N6-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0000154; P:rRNA modification; IEA:InterPro.
DR   HAMAP; MF_01848; -; 1.
DR   InterPro; IPR016909; S-AdoMet-dep_MeTrfase_YbiN_prd.
DR   InterPro; IPR010286; SAM-Mtase_prd.
DR   PANTHER; PTHR13393; DUF890; 1.
DR   Pfam; PF05971; Methyltransf_10; 1.
DR   PIRSF; PIRSF029038; Mtase_YbiN_prd; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    341       Ribosomal RNA large subunit
FT                                methyltransferase F.
FT                                /FTId=PRO_0000349929.
SQ   SEQUENCE   341 AA;  37775 MW;  BC424027E6BB5C90 CRC64;
     MTAPSTPKPS RKKPKPASPA KPATPREKAS LHPRNRHQGR YDFPQLIKST PELGQFVILN
     PYGKESIDFA DPAAVRVFNR ALLKAFYGIA HWDIPADFLC PPVPGRADYV HFLADLLASH
     NQGEIPRGAA VRVLDVGVGA NCIYPLIGYS DYRWQFLGSD IDSTALAAAK AIVQANDLNK
     AISLRQQGNP KQILTGLLDS TERFDLTMCN PPFHASLDEA TRGSQRKWRA LGKADPKRKL
     PVLNFGGQAR ELWCEGGEIR FVSQLISESA SVGQQVLWFS TLVSKASNLP AIESALKKAG
     ALESQVVEMS QGQKQSRFVA WTFKDKAQQQ AWSQERWMRK N
//