Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Glutathione S-transferase

Gene

PFL_2287

Organism
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei30 – 301Glutathione 2Combined sources
Binding sitei57 – 571Glutathione 1Combined sources
Binding sitei152 – 1521Glutathione 2Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

BioCyciPFLU220664:GIX8-2298-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S-transferaseImported (EC:2.5.1.18Imported)
Gene namesi
Ordered Locus Names:PFL_2287Imported
OrganismiPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)Imported
Taxonomic identifieri220664 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000008540 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi220664.PFL_2287.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IKHX-ray2.10A2-234[»]
ProteinModelPortaliQ4KED9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 303Glutathione 1 bindingCombined sources
Regioni70 – 712Glutathione 1 bindingCombined sources
Regioni89 – 902Glutathione 1 bindingCombined sources
Regioni127 – 1282Glutathione 2 bindingCombined sources

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125752.
KOiK00799.
OMAiRYVNESK.
OrthoDBiEOG6677PW.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4KED9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLSAFAVT QKWPAQFPEW IQLYSLPTPN GVKVSIMLEE IGLPYEAHRV
60 70 80 90 100
SFETQDQMTP EFLSVSPNNK IPAILDPHGP GDQPLALFES GAILIYLADK
110 120 130 140 150
SGQLLAQESA ARYETIQWLM FQMGGIGPMF GQVGFFNKFA GREYEDKRPL
160 170 180 190 200
ERYVNEAKRL LGVLDKHLGG REWIMGERYT IADIATFPWI RNLIGFYEAG
210 220 230
ELVGIDNFPE VKRVLAKFVA RPAVIRGLEI PKVS
Length:234
Mass (Da):26,348
Last modified:August 2, 2005 - v1
Checksum:i97F606301F0C9DBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA. Translation: AAY91560.1.
RefSeqiWP_011060585.1. NC_004129.6.

Genome annotation databases

EnsemblBacteriaiAAY91560; AAY91560; PFL_2287.
GeneIDi3475845.
KEGGipfl:PFL_2287.
PATRICi19873841. VBIPseFlu72549_2326.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA. Translation: AAY91560.1.
RefSeqiWP_011060585.1. NC_004129.6.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IKHX-ray2.10A2-234[»]
ProteinModelPortaliQ4KED9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220664.PFL_2287.

Protocols and materials databases

DNASUi3475845.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY91560; AAY91560; PFL_2287.
GeneIDi3475845.
KEGGipfl:PFL_2287.
PATRICi19873841. VBIPseFlu72549_2326.

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125752.
KOiK00799.
OMAiRYVNESK.
OrthoDBiEOG6677PW.

Enzyme and pathway databases

BioCyciPFLU220664:GIX8-2298-MONOMER.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pf-5 / ATCC BAA-477Imported.
  2. "Crystal structure of a glutathione transferase family member from Pseudomonas fluorescens pf-5, target efi-900003, with two glutathione bound."
    Enzyme Function Initiative (EFI)
    Vetting M.W., Sauder J.M., Morisco L.L., Wasserman S.R., Sojitra S., Imker H.J., Burley S.K., Armstrong R.N., Gerlt J.A., Almo S.C.
    Submitted (DEC-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 2-234 IN COMPLEX WITH GLUTATHIONE.

Entry informationi

Entry nameiQ4KED9_PSEF5
AccessioniPrimary (citable) accession number: Q4KED9
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: July 22, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.