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Q4KC81 (ARND_PSEF5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD

EC=3.5.1.n3
Gene names
Name:arnD
Ordered Locus Names:PFL_3046
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01870

Catalytic activity

4-deoxy-4-formamido-beta-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + H2O = 4-amino-4-deoxy-alpha-L-arabinose di-trans,poly-cis-undecaprenyl phosphate + formate. HAMAP-Rule MF_01870

Pathway

Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2. HAMAP-Rule MF_01870

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP-Rule MF_01870

Sequence similarities

Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.

Contains 1 NodB homology domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 294294Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD HAMAP-Rule MF_01870
PRO_0000383523

Regions

Domain1 – 259259NodB homology

Sequences

Sequence LengthMass (Da)Tools
Q4KC81 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 2465DFD81D48E535

FASTA29432,462
        10         20         30         40         50         60 
MQAGLRIDVD TYRGTREGVP RLLESLDEAG VKATFFFSVG PDNMGRHLWR LIRPQFLWKM 

        70         80         90        100        110        120 
LRSNAAGLYG WDILLAGTAW PGKPIGRDLG HLMRQTLAAG HEVGLHAWDH HGWQANTGRW 

       130        140        150        160        170        180 
SQAQLIEQIR RGVDSLNDIL GQAVSCSASA GWRADERVIE AKQQFGFRYN SDCRGQSLFL 

       190        200        210        220        230        240 
PRLADGSLGA PQIPVDLPTF DEVVGPVVAA KDFNSYILDR FSPDKLNVYT VHAEVEGILM 

       250        260        270        280        290 
ANDFRQLLAS ARQRDIHFQP LGNMLPADLA SLPAGKVVRG ALEGREGWLG VQGA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000076 Genomic DNA. Translation: AAY92316.1.
RefSeqYP_260152.1. NC_004129.6.

3D structure databases

ProteinModelPortalQ4KC81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING220664.PFL_3046.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY92316; AAY92316; PFL_3046.
GeneID3475939.
KEGGpfl:PFL_3046.
PATRIC19875403. VBIPseFlu72549_3106.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0726.
HOGENOMHOG000261199.
KOK13014.
OMALHAWDHF.
OrthoDBEOG6423D0.
ProtClustDBPRK15394.

Enzyme and pathway databases

BioCycPFLU220664:GIX8-3060-MONOMER.
UniPathwayUPA00030.
UPA00036; UER00496.

Family and domain databases

Gene3D3.20.20.370. 2 hits.
HAMAPMF_01870. ArnD.
InterProIPR023557. ArnD.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. Polysac_deacetylase.
[Graphical view]
PfamPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMSSF88713. SSF88713. 2 hits.
PROSITEPS51677. NODB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARND_PSEF5
AccessionPrimary (citable) accession number: Q4KC81
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: August 2, 2005
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways