arnT2

Functionⁱ

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

Catalytic activityⁱ

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

Pathwayⁱ: 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis

This protein is involved in the pathway 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis, which is part of Lipopolysaccharide metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis and in Lipopolysaccharide metabolism.

GO - Molecular functionⁱ

4-amino-4-deoxy-L-arabinose transferase activity Source: UniProtKB-EC
mannosyltransferase activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

lipid A biosynthetic process Source: UniProtKB-KW
lipopolysaccharide biosynthetic process Source: UniProtKB-KW
protein O-linked glycosylation Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Glycosyltransferase, Transferase
Biological process	Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCycⁱ	PPRO220664:G1G4K-4589-MONOMER.
UniPathwayⁱ	UPA00037.

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT83. Glycosyltransferase Family 83.

CAZyⁱ

GT83. Glycosyltransferase Family 83.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2UniRule annotation (EC:2.4.2.43UniRule annotation) Alternative name(s): 4-amino-4-deoxy-L-arabinose lipid A transferase 2UniRule annotation Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation Undecaprenyl phosphate-alpha-L-Ara4N transferase 2UniRule annotation
Gene namesⁱ	Name:arnT2UniRule annotation Ordered Locus Names:PFL_4461
Organismⁱ	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Taxonomic identifierⁱ	220664 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas fluorescens group › Pseudomonas protegens
Proteomesⁱ	UP000008540 Componentⁱ: Chromosome

Subcellular locationⁱ

Cell inner membrane
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01165
; Multi-pass membrane protein
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01165

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	42 – 62	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	113 – 135	HelicalUniRule annotationAdd BLAST	23
Transmembraneⁱ	145 – 165	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	166 – 186	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	209 – 229	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	241 – 261	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	290 – 310	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	321 – 341	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	345 – 365	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	380 – 400	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	409 – 429	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	440 – 460	HelicalUniRule annotationAdd BLAST	21

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
plasma membrane Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cell inner membrane, Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000380020	1 – 583	Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2Add BLAST		583

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	220664.PFL_4461.

STRINGⁱ

220664.PFL_4461.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the glycosyltransferase 83 family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG4105SA9. Bacteria. COG1807. LUCA.
HOGENOMⁱ	HOG000273002.
KEGG Orthology (KO) More...KOⁱ	K07264.
OMAⁱ	NTWGELE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00H0.

Family and domain databases

HAMAPⁱ	MF_01165. ArnT_transfer. 1 hit.
InterProⁱ	View protein in InterPro IPR022839. ArnT_tfrase. IPR003342. Glyco_trans_39/83.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02366. PMT. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q4K884-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTSRIQMHRT SPPPAYGTSA PPSGFTLGAS TTSTLQRWAL PLLLVAFGLF 
        60         70         80         90        100
YLLPLTSHGL WIPDETRYAQ ISQEMLLSGD WVAPHFMGIR YFEKPIAGYW 
       110        120        130        140        150
LIAIGQAVFG DNLFGVRIAS ALSTGLSVLL AYLITRRMWN DPRKSFAAAL 
       160        170        180        190        200
LYMSFGLIAG QAGYSNLDPQ FTLWVNLSLV ALWFALDGRS TRERLLAWAG 
       210        220        230        240        250
LGVACGMGFM TKGFLAWLLP VLIALPYMIW QRRLGELVRY GLVAVLVAIG 
       260        270        280        290        300
ISLPWVLSIH AHEPDFWRFF FWHEHIRRFA ADNAQHTRPW WFYLPLLVAS 
       310        320        330        340        350
SLPWAALLPG TFMQAWKDKR QAPTGFLLLW FLLPLAFFSL SRGKLPTYIM 
       360        370        380        390        400
PCLLPLAVLM GSALIDRINA IQGRSIRINS LLNLLIGVAA MVALLYIQLT 
       410        420        430        440        450
RPVYGHNEML GLSLVFIMLM GWIIANLLPA ARPLQYWPAP ALGIWLLVAL 
       460        470        480        490        500
LPAGMPGFIV HNQMPDQFIK EHIEELRQTK TLLSNDLGAA SALAWRLQRP 
       510        520        530        540        550
EVTLYNTEGE LKYGLAYADS AQRKVSMAEV GQWVSEARKQ GSVGVVMRVK 
       560        570        580 
DVVESEEVAL LPPGGKRYEE GNMLVLILPQ SQP

Length:583

Mass (Da):65,170

Last modified:August 2, 2005 - v1

Checksum:ⁱF9231E122AABDCED

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000076 Genomic DNA. Translation: AAY93712.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011062724.1. NC_004129.6.

Genome annotation databases

EnsemblBacteriaⁱ	AAY93712; AAY93712; PFL_4461.
KEGGⁱ	pfl:PFL_4461.
PATRICⁱ	fig\|220664.5.peg.4566.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q4K884	A0A2K2X166 A0A2K4M4E7 A0A1K1VTY5 UPI0003721D09 UPI000596FA2C UPI000641C66C UPI00064361CB UPI00069CE439 UPI00069DDFB9 UPI00080700BA +4	Pseudomonas protegens Pseudomonas sp. NFPP09 Pseudomonas fluorescens Pseudomonas Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CHA0)	583	UniRef90_Q4K884	Cluster: Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2	15

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q4K884	UPI00069CE439 UPI00064361CB A0A2K2X166 UPI000596FA2C UPI00069DDFB9 UPI0003721D09 UPI000641C66C UPI00080700BA UPI000931D28D A0A2K4M4E7 +81	Pseudomonas protegens Pseudomonas fluorescens Pseudomonas Pseudomonas sp. NFPP09 Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CHA0) Pseudomonas sp. ACN8 Pseudomonas sp. B28(2017) Pseudomonas sp. GM33 Pseudomonas sp. GM49 Pseudomonas sp. R37(2017) And more	583	UniRef50_Q4K884	Cluster: Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2	92

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000076 Genomic DNA. Translation: AAY93712.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011062724.1. NC_004129.6.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	220664.PFL_4461.

STRINGⁱ

220664.PFL_4461.

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT83. Glycosyltransferase Family 83.

CAZyⁱ

GT83. Glycosyltransferase Family 83.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAY93712; AAY93712; PFL_4461.
KEGGⁱ	pfl:PFL_4461.
PATRICⁱ	fig\|220664.5.peg.4566.

Phylogenomic databases

eggNOGⁱ	ENOG4105SA9. Bacteria. COG1807. LUCA.
HOGENOMⁱ	HOG000273002.
KEGG Orthology (KO) More...KOⁱ	K07264.
OMAⁱ	NTWGELE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00H0.

Enzyme and pathway databases

UniPathwayⁱ	UPA00037.
BioCycⁱ	PPRO220664:G1G4K-4589-MONOMER.

Family and domain databases

HAMAPⁱ	MF_01165. ArnT_transfer. 1 hit.
InterProⁱ	View protein in InterPro IPR022839. ArnT_tfrase. IPR003342. Glyco_trans_39/83.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02366. PMT. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ARNT2_PSEF5
Accessionⁱ	Q4K884Primary (citable) accession number: Q4K884
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
	Last sequence update:	August 2, 2005
	Last modified:	March 28, 2018
	This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q4K884 (ARNT2_PSEF5)

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Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ