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Q4K841 (Q4K841_PSEF5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6,7-dimethyl-8-ribityllumazine synthase 1 HAMAP MF_00178
Short name=DMRL synthase 1 HAMAP MF_00178
Short name=Lumazine synthase 1 HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178
Alternative name(s):
Riboflavin synthase beta chain 1 HAMAP MF_00178
Gene names
Name:ribH1 HAMAP MF_00178
Synonyms:ribH EMBL AAY93755.1
Ordered Locus Names:PFL_4508
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178

Sequence similarities

Belongs to the DMRL synthase family. HAMAP MF_00178

Ontologies

Keywords
   Biological processRiboflavin biosynthesis HAMAP MF_00178
   Molecular functionTransferase HAMAP MF_00178 EMBL AAY93755.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processriboflavin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentriboflavin synthase complex

Inferred from electronic annotation. Source: InterPro

   Molecular functionriboflavin synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q4K841 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: E3AB84B029575924

FASTA16918,996
        10         20         30         40         50         60 
MQPTAIDSKS KHHPNERVAF IQACWHKEIV DQSRQGFVTE MLAQGYQESD IDFFEVGGAF 

        70         80         90        100        110        120 
EIPLHAKLLA KSGRYTGIVA AGLVVDGGIY RHEFVAQSVI SGLMQVQLET EVPVFSVVLT 

       130        140        150        160 
PHHFHAGEEH QKFFFEHFVH KGQEAARTCA DTLQKVRALR RNEQRAVAV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000076 Genomic DNA. Translation: AAY93755.1.
RefSeqYP_261592.1. NC_004129.6.

3D structure databases

ProteinModelPortalQ4K841.
SMRQ4K841. Positions 17-146.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4K841.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3478623.
GenomeReviewsGene locus PFL_4508 in contig CP000076_GR.
KEGGpfl:PFL_4508.
NMPDRfig|220664.3.peg.5003.
PATRIC19878448. VBIPseFlu72549_4609.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0054.
HOGENOMHBG311126.
OMARRYTAIV.
PhylomeDBQ4K841.
ProtClustDBPRK12419.

Enzyme and pathway databases

BioCycPFLU220664:PFL_4508-MONOMER.

Family and domain databases

HAMAPMF_00178. Lumazine_synth.
[Tree]
InterProIPR002180. DMRL_synthase.
[Graphical view]
Gene3DG3DSA:3.40.50.960. DMRL_synthase. 1 hit.
KOK00794.
PANTHERPTHR21058. DMRL_synthase. 1 hit.
PfamPF00885. DMRL_synthase. 1 hit.
[Graphical view]
SUPFAMSSF52121. DMRL_synthase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ4K841_PSEF5
AccessionPrimary (citable) accession number: Q4K841
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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