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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-1,6-bisphosphate aldolase (fba)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei359Proton donorUniRule annotation1
Active sitei390UniRule annotation1
Active sitei518UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPPRO220664:G1G4K-5447-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PFL_5280
OrganismiPseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Taxonomic identifieri220664 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000008540 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807101 – 554Glucose-6-phosphate isomeraseAdd BLAST554

Proteomic databases

PRIDEiQ4K5Y1

Interactioni

Protein-protein interaction databases

STRINGi220664.PFL_5280

Structurei

3D structure databases

ProteinModelPortaliQ4K5Y1
SMRiQ4K5Y1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q4K5Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYYRTPHDV TALPAWQALK DHRQAMQDFS MREAFNADPQ RFSQFTLSSC
60 70 80 90 100
GLFLDYSKNL ITSETRDLLV NLAKEVGLSD AIKSMITGEL VNASEGRPAL
110 120 130 140 150
HTALRRPVGD KLSVNGVNVM PEVHKVLNQI TELVGRIHDG LWRGYTEKPI
160 170 180 190 200
TDVVNIGIGG SFLGPELVSE ALLSYAQKGV RCHYLANIDG SEFHELSAKI
210 220 230 240 250
RAETTLFIVS SKSFNTLETL KNAQAARAWY LAQGGSEAEL HRHFIAVSSN
260 270 280 290 300
NAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG MSNFKELLSG
310 320 330 340 350
AYTMDQHFQS APFEQNMPVL LALLGVWYGN FWGAQSHAIL PYDHYLRNIT
360 370 380 390 400
KHLQQLDMES NGKSVRQDGT PVATDTGPVI WGGVGCNGQH AYHQLLHQGT
410 420 430 440 450
QLIPADFIVP IVSFNPVADH HQWLYANCLS QSQALMLGKT RAEAESELRE
460 470 480 490 500
KGLSEAEIAK LAPHKVIPGN RPSNTLVVER ISPRRLGALV ALYEHKVFVQ
510 520 530 540 550
SVVWGINAFD QWGVELGKEL GKGVYNRLVG SDETLADDAS TQGLINYFRG

RHRG
Length:554
Mass (Da):61,270
Last modified:August 2, 2005 - v1
Checksum:i88B0692FC395C17D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA Translation: AAY94494.1
RefSeqiWP_011063513.1, NC_004129.6

Genome annotation databases

EnsemblBacteriaiAAY94494; AAY94494; PFL_5280
GeneIDi29827826
KEGGipfl:PFL_5280
PATRICifig|220664.5.peg.5392

Similar proteinsi

Entry informationi

Entry nameiG6PI_PSEF5
AccessioniPrimary (citable) accession number: Q4K5Y1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: August 2, 2005
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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