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Q4K5Y0 (Q4K5Y0_PSEF5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase 2 HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase 2 HAMAP MF_01123
Acyl-activating enzyme 2 HAMAP MF_01123
Gene names
Name:acsA_2 EMBL AAY94495.1
Synonyms:acsA2 HAMAP MF_01123
Ordered Locus Names:PFL_5281
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length645 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5141 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6061N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
Q4K5Y0 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 8B151AD6681D7F6C

FASTA64571,544
        10         20         30         40         50         60 
MFDISTFPKA DAVRRAAQMS QDDYHHLYRQ SIEQPDQFWA EQARRFLHWS SPWDSVHSHD 

        70         80         90        100        110        120 
MRTGEANWFR GGQLNVSYNC IDRHLEKRGN QAAIIWEGDN PADSQRITYQ ELHDRVCRLA 

       130        140        150        160        170        180 
NVLKSRGVKK GDRVCIYMPM IPEVAYAMLA CTRIGAVHSV VFGGFSPEAL RDRILNADCR 

       190        200        210        220        230        240 
TVITADEGVR GGKLIPLKSN VDKALLSCPD VSSVLVVERT RNPVNWVPDR DISYEQAVAG 

       250        260        270        280        290        300 
ASNQCAPEPM DAEDPLFILY TSGSTGKPKG VLHTTGGYLL QAAMTFKYVL DYRDGEVFWC 

       310        320        330        340        350        360 
TADVGWVTGH SYILYGPLAN GATTLIFEGV PNYPSTSRFW EVVDKHQVNI FYTAPTALRA 

       370        380        390        400        410        420 
LMREGSAPLQ NTSRASLRLL GSVGEPINPE AWEWYFNVVG EQRCPIVDTW WQTETGGIML 

       430        440        450        460        470        480 
SPLVSARQIK PGCASTPMFG VQPVLLDDQG KEIHGAGSGI LAIKASWPAQ IRSVYGDPKR 

       490        500        510        520        530        540 
MVETYFAPYP GYYFTGDGAR RDEDGSYWIT GRIDDVINVS GHRIGTAEVE SALVLHDSIA 

       550        560        570        580        590        600 
EAAVVGYPHD LKGQGIYAFV TPMQGVEPDE ALKKELLALV SREIGSFAKP ELIQWAPALP 

       610        620        630        640 
KTRSGKIMRR ILRKIACNEL DTLGDTSTLA DPSVVDGLID KRLNV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000076 Genomic DNA. Translation: AAY94495.1.
RefSeqYP_262353.1. NC_004129.6.

3D structure databases

ProteinModelPortalQ4K5Y0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4K5Y0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3479677.
GenomeReviewsGene locus PFL_5281 in contig CP000076_GR.
KEGGpfl:PFL_5281.
NMPDRfig|220664.3.peg.683.
PATRIC19880037. VBIPseFlu72549_5393.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMAHQRMVDT.
PhylomeDBQ4K5Y0.
ProtClustDBPRK00174.

Enzyme and pathway databases

BioCycPFLU220664:PFL_5281-MONOMER.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4K5Y0_PSEF5
AccessionPrimary (citable) accession number: Q4K5Y0
Entry history
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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