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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPPRO220664:G1G4K-5530-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:PFL_5361
OrganismiPseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Taxonomic identifieri220664 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000008540 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003664761 – 374Ribosomal RNA large subunit methyltransferase GAdd BLAST374

Interactioni

Protein-protein interaction databases

STRINGi220664.PFL_5361

Structurei

3D structure databases

ProteinModelPortaliQ4K5Q4
SMRiQ4K5Q4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J Bacteria
COG2813 LUCA
HOGENOMiHOG000246323
KOiK11391
OMAiNLQAWDA
OrthoDBiPOG091H05RK

Family and domain databases

HAMAPiMF_01859 23SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR017237 rRNA_m2G-MeTrfase_RsmD
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PANTHERiPTHR18895:SF6 PTHR18895:SF6, 1 hit
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PIRSFiPIRSF037565 RRNA_m2G_Mtase_RsmD_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

Q4K5Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLASPFAQ LDLIRQPEQQ NEPLQAFDAA DEYLLNHLAE QQPASDTRVL
60 70 80 90 100
VLNDSFGALA ASLLGKVQVS SSGDSYLGAL ALEKNLVRNG LPFDAVRVVP
110 120 130 140 150
ASEPLAGPFD RVLIRVPKTL ALLEEQLIRL QGQLAPGAQV VAAAMVKHLP
160 170 180 190 200
RAAGDLLERY IGPVQASLAV KKARLLIATP QDKQPVVSPY PTRYRLEQPA
210 220 230 240 250
IELLNHANVF CREGLDIGTR AFLPHLPQNL GSARVADLGC GNGVLAIASA
260 270 280 290 300
LDNPQAHYTL VDESFMAVQS ARENWQAVLG EREAQMRAGD GLAGQAAQSL
310 320 330 340 350
EVVLCNPPFH QQQVVGDFLA WRMFQQAREA LVVGGALYIV GNRHLGYHSK
360 370
LARLFRGVEQ VAATPKFVIL KARK
Length:374
Mass (Da):40,526
Last modified:August 2, 2005 - v1
Checksum:iFE3C362C0AECC547
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA Translation: AAY94571.1
RefSeqiWP_011063585.1, NC_004129.6

Genome annotation databases

EnsemblBacteriaiAAY94571; AAY94571; PFL_5361
KEGGipfl:PFL_5361
PATRICifig|220664.5.peg.5474

Similar proteinsi

Entry informationi

Entry nameiRLMG_PSEF5
AccessioniPrimary (citable) accession number: Q4K5Q4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: August 2, 2005
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health