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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciPPRO220664:G1G4K-5821-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:PFL_5651
OrganismiPseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Taxonomic identifieri220664 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000008540 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120781 – 289Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST289

Interactioni

Protein-protein interaction databases

STRINGi220664.PFL_5651

Structurei

3D structure databases

ProteinModelPortaliQ4K4X3
SMRiQ4K4X3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q4K4X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYAVGDLQ GCLEPLQCLL EQVAFDPARD RLWLVGDLVN RGPQSLETLR
60 70 80 90 100
YLYSIRDSLV CVLGNHDLHL LAVWRNVERL KKSDTLREIL EAPDCEELLQ
110 120 130 140 150
WLRQQKLMHY DEARNIAMVH AGIAPQWSLK KAQKCAAEVE EALRDDNLFD
160 170 180 190 200
PFLDGMYGND PAKWDSDLKG VTRLRVITNY FTRMRFCTSD GKLDLKSKEG
210 220 230 240 250
LDTAPPGYAP WFSHKERKTR DLKIIFGHWA ALEGHCNEPG IFALDSGCVW
260 270 280
GGAMTLLNVD SGVRLTCDCD AQGRTAALSP DPLPAPAKR
Length:289
Mass (Da):32,526
Last modified:August 2, 2005 - v1
Checksum:iBB302E6FE829B4A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000076 Genomic DNA Translation: AAY94844.1
RefSeqiWP_011063829.1, NC_004129.6

Genome annotation databases

EnsemblBacteriaiAAY94844; AAY94844; PFL_5651
KEGGipfl:PFL_5651
PATRICifig|220664.5.peg.5763

Similar proteinsi

Entry informationi

Entry nameiAPAH_PSEF5
AccessioniPrimary (citable) accession number: Q4K4X3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health