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Reviewed, UniProtKB/Swiss-Prot Q4K4K7 (BETA_PSEF5)

Last modified June 16, 2009. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Choline dehydrogenase
      Short name=CHD
      Short name=CDH
    EC=1.1.99.1
Gene names
Name: betA
Ordered Locus Names: PFL_5768
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

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Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity.

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity.

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 567567Choline dehydrogenase HAMAP MF_00750
PRO_0000258928

Regions

Nucleotide binding6 – 3530FAD Probable

Sites

Active site4751 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q4K4K7-1 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 513BE86614467644

FASTA56762,704
        10         20         30         40         50         60 
MAQEYDYIIV GAGSAGNTLA TRLTEDEGVT VLLLEAGGPD YRFDFRTQMP AALAFPLQGR 

        70         80         90        100        110        120 
RYNWAYETDP EPHMNGRRME CGRGKGLGGS SLINGMCYIR GNAMDYDGWA KLPGLEDWTY 

       130        140        150        160        170        180 
LDCLPYFRKA ETRDIGPNDY HGGEGPVSVT TPKAGNNPLF HAMVEAGVQA GYPRTEDLNG 

       190        200        210        220        230        240 
YQQEGFGPMD RTVTPKGRRA STARGYLDTA KKRSTLTIVT HALTDKILFE GKRAVGVSYL 

       250        260        270        280        290        300 
QGSTEERVEA RARKEVIVSS GAIASPQLLQ RSGVGPRALL ESLDIPVVHD LPGVGENLQD 

       310        320        330        340        350        360 
HLELYLQYAC TQPVSLYPSL LWWNQPAIGA EWLFNGTGIG ASNQFEAGGF IRTREEFEWP 

       370        380        390        400        410        420 
NIQYHFLPVA INYNGSNGVK EHGFQAHMGS MRSPSRGRVQ LKSKDPRQHP SILFNYMATE 

       430        440        450        460        470        480 
QDWQEFRDGI RLTREIMQQP ALDPFRGREI SPGIEVQTDE QLDKFVREHA ETAFHPSCSC 

       490        500        510        520        530        540 
KMGTDDMAVV DGQGRVHGMQ GLRVVDASIM PIITTGNLNA PTIMMAEKIA DKIRGRQPLP 

       550        560 
RSTAAYYVAG EAPVRGKPMR DVTPAAQ

« Hide

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Cross-references

Sequence databases

CP000076 Genomic DNA. Translation: AAY94958.1.
RefSeqYP_262826.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3480140.
GenomeReviewsGene locus PFL_5768 in contig CP000076_GR.
KEGGpfl:PFL_5768.
NMPDRfig|220664.3.peg.15.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ4K4K7.
OMAQ4K4K7. GRRMECG.

Enzyme and pathway databases

BioCycPFLU220664:PFL_5768-MON.

Family and domain databases

HAMAPMF_00750.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. betA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameBETA_PSEF5
AccessionPrimary (citable) accession number: Q4K4K7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: August 2, 2005
Last modified: June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents