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Q4K434 (ARGA_PSEF5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Amino-acid acetyltransferase
EC=2.3.1.1
Alternative name(s):
N-acetylglutamate synthase
Short name=AGS
Short name=NAGS
Gene names
Name:argA
Ordered Locus Names:PFL_5941
OrganismPseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [Complete proteome] [HAMAP]
Taxonomic identifier220664 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01105

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01105

Subcellular location

Cytoplasm By similarity HAMAP MF_01105.

Sequence similarities

Belongs to the acetyltransferase family. ArgA subfamily.

Contains 1 N-acetyltransferase domain.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacetyl-CoA:L-glutamate N-acetyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 432432Amino-acid acetyltransferase HAMAP MF_01105
PRO_1000084817

Regions

Domain286 – 425140N-acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q4K434 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 685EEAB2C2D5B927

FASTA43247,675
        10         20         30         40         50         60 
MPEYVNWLRH ASPYINAHRD CTFVVMLPGD GVEHPNFGNI VHDLVLLHSL GVRLVLVHGS 

        70         80         90        100        110        120 
RPQIEARLAA RGLTPHYHHG LRITDAATLE CVIDAVGQLR IAIEARLSMD MASSPMQGSR 

       130        140        150        160        170        180 
LRVASGNLVT ARPIGVLEGV DYHHTGEVRR VDRKGINRLL DERSIVLLSP LGYSPTGETF 

       190        200        210        220        230        240 
NLACEDVATR AAIDLGADKL LLFGADPGLL DENGKLVREL RPQQVPAHLQ RLGGNYQAEL 

       250        260        270        280        290        300 
LDAAAEACRG GVGRSHIVSY AEDGALLTEL FTRDGGGTLV AQEQFERVRE AAIEDVGGLL 

       310        320        330        340        350        360 
ELISPLEEQG ILVRRSREVL EREIEQFSVV EREGMIIACA ALYQIADSDA GELACLAVNP 

       370        380        390        400        410        420 
EYRHGKRGDE LLERIETRAR AQGLKTLFVL TTRTAHWFRE RGFVPSSVER LPSARASLYN 

       430 
YQRNSKIFEK AL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000076 Genomic DNA. Translation: AAY95131.1.
RefSeqYP_262999.1. NC_004129.6.

3D structure databases

HSSPHSSP built from PDB template 2BUF based on UniProtKB Q9HTN2.
ProteinModelPortalQ4K434.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4K434.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3480313.
GenomeReviewsGene locus PFL_5941 in contig CP000076_GR.
KEGGpfl:PFL_5941.
NMPDRfig|220664.3.peg.1134.
PATRIC19881393. VBIPseFlu72549_6057.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0548.
HOGENOMHBG545264.
OMAAFNLAME.
PhylomeDBQ4K434.
ProtClustDBPRK05279.

Enzyme and pathway databases

BioCycPFLU220664:PFL_5941-MONOMER.

Family and domain databases

HAMAPMF_01105. N-acetyl_glu_synth.
[Tree]
InterProIPR000182. AcTrfase_GCN5-related_dom.
IPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR010167. NH2A_AcTrfase_ArgA.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KOK14682.
PfamPF00696. AA_kinase. 1 hit.
PF00583. Acetyltransf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000423. ArgA. 1 hit.
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMsTIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARGA_PSEF5
AccessionPrimary (citable) accession number: Q4K434
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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