Q4JXY1 (DCD_CORJK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	jk0174

Organism

Corynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]

Taxonomic identifier

306537 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009713

Sequences

	Sequence		Length	Mass (Da)
	Q4JXY1 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 6F55874413AFEC09	FASTA	188	20,350
	10 20 30 40 50 60 MLLSDRDIRA AINSGELKID PHDDQMVQPS SIDVRLDGLF RVFNNSKYTH IDPKQPQEEL 70 80 90 100 110 120 TTLVEVPDDE AFILHPGEFV LGATLECFGI PAHLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFTGHITLEL SNTANLPIAL YPGMKIGQLA LFTMTSPAEA PYGSGTLGSK YQGQRGPTPS KAYLNFQN

References

[1]

"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora." Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A. J. Bacteriol. 187:4671-4682(2005) [PubMed: 15968079] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K411.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR931997 Genomic DNA. Translation: CAI36326.1.
RefSeq	YP_249944.1. NC_007164.1.
3D structure databases
ProteinModelPortal	Q4JXY1.
SMR	Q4JXY1. Positions 1-186.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4JXY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3433765.
GenomeReviews	Gene locus jk0174 in contig CR931997_GR.
KEGG	cjk:jk0174.
NMPDR	fig|306537.3.peg.247.
PATRIC	21511208. VBICorJei31838_0186.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CJEI306537:JK0174-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CORJK

Accession

Primary (citable) accession number: Q4JXY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program