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Q4JX51

- G6PI_CORJK

UniProt

Q4JX51 - G6PI_CORJK

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, jk0449
Organism
Corynebacterium jeikeium (strain K411)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei373 – 3731Proton donor By similarity
Active sitei404 – 4041 By similarity
Active sitei530 – 5301 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCJEI306537:GJ8V-466-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:jk0449
OrganismiCorynebacterium jeikeium (strain K411)
Taxonomic identifieri306537 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000545: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 565565Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180634Add
BLAST

Proteomic databases

PRIDEiQ4JX51.

Interactioni

Protein-protein interaction databases

STRINGi306537.jk0449.

Structurei

3D structure databases

ProteinModelPortaliQ4JX51.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4JX51-1 [UniParc]FASTAAdd to Basket

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MPQQRETAHK TREWKKLTEY ADATRGTQLR ELFTEQPGRS SDMTYNVGPL    50
HVDLSKNLID ERGLRLLLDL ARARGLEDYR SAMFDGEHIN TTEDRAVLHT 100
ALRIPVDREF SIPVGADETQ DVAADVHAVL GRMRDFAKAL RSGSWQGVTG 150
HTIKHVVNIG IGGSDLGPAM AAQALRPYMT AGITPHFISN IDPADVAGTL 200
DGLDAESTLF VIASKTFTTS ETLANAHAAR RWLLRNLADA GVDVEGDDAI 250
RDITAKHFVA VSTAAEKVQE FGIDTKNMFE FWDWVGGRYS VDSAIGLSLM 300
AAIGPQDFMR FLEGFHEVDD HFRTEPLEMN IPVLMGMLGV WYTDFLGAQS 350
HAVLPYSEDM ARFPAYLQQL TMESNGKSVQ LDGTPVEVPS GEIYWGEPGT 400
NGQHAFFQLL HQGTHLVPAD FIGFVNPHDD AVAADGTTSM HDMLMSNFFA 450
QTRVLAFGKN AEELKEEGVA PELIPHKVMP GNRPTTTILA NKLTPKTLGA 500
LIALYEHIVF VQGVIWGINS FDQWGVELGK KQANALLPAV TGAERSDAGD 550
SSTDDLIAYY RQHRD 565
Length:565
Mass (Da):62,145
Last modified:November 8, 2005 - v2
Checksum:i9F29941754A17F44
GO

Sequence cautioni

The sequence CAI36606.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR931997 Genomic DNA. Translation: CAI36606.1. Different initiation.
RefSeqiYP_250224.1. NC_007164.1.

Genome annotation databases

EnsemblBacteriaiCAI36606; CAI36606; jk0449.
GeneIDi3432390.
KEGGicjk:jk0449.
PATRICi21511780. VBICorJei31838_0461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR931997 Genomic DNA. Translation: CAI36606.1 . Different initiation.
RefSeqi YP_250224.1. NC_007164.1.

3D structure databases

ProteinModelPortali Q4JX51.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 306537.jk0449.

Proteomic databases

PRIDEi Q4JX51.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI36606 ; CAI36606 ; jk0449 .
GeneIDi 3432390.
KEGGi cjk:jk0449.
PATRICi 21511780. VBICorJei31838_0461.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci CJEI306537:GJ8V-466-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora."
    Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A.
    J. Bacteriol. 187:4671-4682(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K411.

Entry informationi

Entry nameiG6PI_CORJK
AccessioniPrimary (citable) accession number: Q4JX51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: June 11, 2014
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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