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Q4JX51 (G6PI_CORJK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:jk0449
OrganismCorynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]
Taxonomic identifier306537 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length565 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Sequence caution

The sequence CAI36606.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 565565Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180634

Sites

Active site3731Proton donor By similarity
Active site4041 By similarity
Active site5301 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4JX51 [UniParc].

Last modified November 8, 2005. Version 2.
Checksum: 9F29941754A17F44

FASTA56562,145
        10         20         30         40         50         60 
MPQQRETAHK TREWKKLTEY ADATRGTQLR ELFTEQPGRS SDMTYNVGPL HVDLSKNLID 

        70         80         90        100        110        120 
ERGLRLLLDL ARARGLEDYR SAMFDGEHIN TTEDRAVLHT ALRIPVDREF SIPVGADETQ 

       130        140        150        160        170        180 
DVAADVHAVL GRMRDFAKAL RSGSWQGVTG HTIKHVVNIG IGGSDLGPAM AAQALRPYMT 

       190        200        210        220        230        240 
AGITPHFISN IDPADVAGTL DGLDAESTLF VIASKTFTTS ETLANAHAAR RWLLRNLADA 

       250        260        270        280        290        300 
GVDVEGDDAI RDITAKHFVA VSTAAEKVQE FGIDTKNMFE FWDWVGGRYS VDSAIGLSLM 

       310        320        330        340        350        360 
AAIGPQDFMR FLEGFHEVDD HFRTEPLEMN IPVLMGMLGV WYTDFLGAQS HAVLPYSEDM 

       370        380        390        400        410        420 
ARFPAYLQQL TMESNGKSVQ LDGTPVEVPS GEIYWGEPGT NGQHAFFQLL HQGTHLVPAD 

       430        440        450        460        470        480 
FIGFVNPHDD AVAADGTTSM HDMLMSNFFA QTRVLAFGKN AEELKEEGVA PELIPHKVMP 

       490        500        510        520        530        540 
GNRPTTTILA NKLTPKTLGA LIALYEHIVF VQGVIWGINS FDQWGVELGK KQANALLPAV 

       550        560 
TGAERSDAGD SSTDDLIAYY RQHRD 

« Hide

References

[1]"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora."
Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A.
J. Bacteriol. 187:4671-4682(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K411.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR931997 Genomic DNA. Translation: CAI36606.1. Different initiation.
RefSeqYP_250224.1. NC_007164.1.

3D structure databases

ProteinModelPortalQ4JX51.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING306537.jk0449.

Proteomic databases

PRIDEQ4JX51.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI36606; CAI36606; jk0449.
GeneID3432390.
KEGGcjk:jk0449.
PATRIC21511780. VBICorJei31838_0461.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycCJEI306537:GJ8V-466-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CORJK
AccessionPrimary (citable) accession number: Q4JX51
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: February 19, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways