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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Corynebacterium jeikeium (strain K411)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei373 – 3731Proton donorUniRule annotation
Active sitei404 – 4041UniRule annotation
Active sitei530 – 5301UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCJEI306537:GJ8V-466-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:jk0449
OrganismiCorynebacterium jeikeium (strain K411)
Taxonomic identifieri306537 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000545 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 565565Glucose-6-phosphate isomerasePRO_0000180634Add
BLAST

Proteomic databases

PRIDEiQ4JX51.

Interactioni

Protein-protein interaction databases

STRINGi306537.jk0449.

Structurei

3D structure databases

ProteinModelPortaliQ4JX51.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4JX51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQQRETAHK TREWKKLTEY ADATRGTQLR ELFTEQPGRS SDMTYNVGPL
60 70 80 90 100
HVDLSKNLID ERGLRLLLDL ARARGLEDYR SAMFDGEHIN TTEDRAVLHT
110 120 130 140 150
ALRIPVDREF SIPVGADETQ DVAADVHAVL GRMRDFAKAL RSGSWQGVTG
160 170 180 190 200
HTIKHVVNIG IGGSDLGPAM AAQALRPYMT AGITPHFISN IDPADVAGTL
210 220 230 240 250
DGLDAESTLF VIASKTFTTS ETLANAHAAR RWLLRNLADA GVDVEGDDAI
260 270 280 290 300
RDITAKHFVA VSTAAEKVQE FGIDTKNMFE FWDWVGGRYS VDSAIGLSLM
310 320 330 340 350
AAIGPQDFMR FLEGFHEVDD HFRTEPLEMN IPVLMGMLGV WYTDFLGAQS
360 370 380 390 400
HAVLPYSEDM ARFPAYLQQL TMESNGKSVQ LDGTPVEVPS GEIYWGEPGT
410 420 430 440 450
NGQHAFFQLL HQGTHLVPAD FIGFVNPHDD AVAADGTTSM HDMLMSNFFA
460 470 480 490 500
QTRVLAFGKN AEELKEEGVA PELIPHKVMP GNRPTTTILA NKLTPKTLGA
510 520 530 540 550
LIALYEHIVF VQGVIWGINS FDQWGVELGK KQANALLPAV TGAERSDAGD
560
SSTDDLIAYY RQHRD
Length:565
Mass (Da):62,145
Last modified:November 8, 2005 - v2
Checksum:i9F29941754A17F44
GO

Sequence cautioni

The sequence CAI36606.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR931997 Genomic DNA. Translation: CAI36606.1. Different initiation.
RefSeqiYP_250224.1. NC_007164.1.

Genome annotation databases

EnsemblBacteriaiCAI36606; CAI36606; jk0449.
KEGGicjk:jk0449.
PATRICi21511780. VBICorJei31838_0461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR931997 Genomic DNA. Translation: CAI36606.1. Different initiation.
RefSeqiYP_250224.1. NC_007164.1.

3D structure databases

ProteinModelPortaliQ4JX51.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi306537.jk0449.

Proteomic databases

PRIDEiQ4JX51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI36606; CAI36606; jk0449.
KEGGicjk:jk0449.
PATRICi21511780. VBICorJei31838_0461.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciCJEI306537:GJ8V-466-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora."
    Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A.
    J. Bacteriol. 187:4671-4682(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K411.

Entry informationi

Entry nameiG6PI_CORJK
AccessioniPrimary (citable) accession number: Q4JX51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: May 27, 2015
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.