Q4JW72 (Q4JW72_CORJK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malto-oligosyltrehalose trehalohydrolase PIRNR PIRNR006337
Short name=MTHase PIRNR PIRNR006337
EC=3.2.1.141 PIRNR PIRNR006337

Alternative name(s):
4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase PIRNR PIRNR006337
Maltooligosyl trehalose trehalohydrolase PIRNR PIRNR006337

Gene names

Name:	treZ EMBL CAI36935.1
Ordered Locus Names:	jk0773

Organism

Corynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]

Taxonomic identifier

306537 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)-alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D-glucan. PIRNR PIRNR006337
Pathway	Glycan biosynthesis; trehalose biosynthesis. PIRNR PIRNR006337
Subcellular location	Cytoplasm By similarity PIRSR PIRSR006337-1.
Sequence similarities	Belongs to the glycosyl hydrolase 13 family. PIRNR PIRNR006337

Ontologies

Keywords
Molecular function	Glycosidase PIRNR PIRNR006337 EMBL CAI36935.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	245	1	Nucleophile By similarity PIRSR PIRSR006337-1
	Active site	274	1	Proton donor By similarity PIRSR PIRSR006337-1
	Site	362	1	Transition state stabilizer By similarity PIRSR PIRSR006337-3

Sequences

	Sequence		Length	Mass (Da)
	Q4JW72 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 3115BC75873F9182	FASTA	567	63,541
	10 20 30 40 50 60 MYSVWAPLAE NVELVLQPAQ TSTGAEQRIP MTREADNWFL AEVPANPGDR YGFSVDGSPV 70 80 90 100 110 120 FPDPRSKRQP DGIHGLSEVW RIDKPRKQLG RPLRGEVLYE LHIGTFTPEG TFDAAIEKLD 130 140 150 160 170 180 ELKAVGVTAI ELMPVQPFGG ERNWGYDGVM WHAVTDVYGG PDGLLRLIDA AHNRDLAVVL 190 200 210 220 230 240 DVVYNHFGPD GNYTGVFGPY TAGGSTGWGD VVNLQGRDSD EVRTYILEAV HQWTQEFGVD 250 260 270 280 290 300 GLRLDAVHAL DDTGAVSLIE QIRDAAEPAW IMAESDQNDP VYTENYKVAQ WNDDIHHAIH 310 320 330 340 350 360 TVVSGEDHAY YSDFGTVEVL ATTFQRVFWH DGRYSSFRGR THGRPVTDPE LWRFVTYTTT 370 380 390 400 410 420 HDQTGNRAAG DRPSMNLSVN QQLAKATLVL TSPFTPMLFM GEEWGASTPF AFFVDHENEE 430 440 450 460 470 480 LNQATREGRM REFARAGWDP KEVPNPAAEE TFRNSVLKWA ERTEHPHAEV LRAYTELLEF 490 500 510 520 530 540 RRTHRLAEAE LLDIRWWADG EEPVSESLAG VNPTVPPVDA ADELAHGRWI ELTYQAPESL 550 560 VKVTVNLADA PHDRLGLGPW EARYSAQ

References

[1]

"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora." Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A. J. Bacteriol. 187:4671-4682(2005) [PubMed: 15968079] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K411.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR931997 Genomic DNA. Translation: CAI36935.1.
RefSeq	YP_250553.1. NC_007164.1.
3D structure databases
ProteinModelPortal	Q4JW72.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4JW72.
Protein family/group databases
CAZy	GH13. Glycoside Hydrolase Family 13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3433458.
GenomeReviews	Gene locus jk0773 in contig CR931997_GR.
KEGG	cjk:jk0773.
NMPDR	fig|306537.3.peg.1632.
PATRIC	21512438. VBICorJei31838_0781.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0296.
HOGENOM	HBG367595.
OMA	EGFVYQG.
ProtClustDB	CLSK2503597.
Family and domain databases
InterPro	IPR015902. Alpha_amylase. IPR006047. Glyco_hydro_13_cat_dom. IPR004193. Glyco_hydro_13_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR012768. Trehalose_TreZ. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
KO	K01236.
PANTHER	PTHR10357. Alpha_amylase. 1 hit. PTHR10357:SF21. PTHR10357:SF21. 1 hit.
Pfam	PF00128. Alpha-amylase. 2 hits. PF02922. CBM_48. 1 hit. [Graphical view]
PIRSF	PIRSF006337. Trehalose_TreZ. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit. SSF81296. Ig_E-set. 1 hit.
TIGRFAMs	TIGR02402. Trehalose_TreZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4JW72_CORJK

Accession

Primary (citable) accession number: Q4JW72

Entry history

Integrated into UniProtKB/TrEMBL:	August 2, 2005
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)