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Protein
Submitted name:

Putative D-alanine-D-alanine ligase

Gene

ddlA1-C

Organism
Corynebacterium jeikeium (strain K411)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative D-alanine-D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Name:ddlA1-CImported
Ordered Locus Names:jk0922Imported
OrganismiCorynebacterium jeikeium (strain K411)Imported
Taxonomic identifieri306537 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000545 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi306537.jk0922.

Structurei

3D structure databases

ProteinModelPortaliQ4JVS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 196ATP-graspInterPro annotationAdd BLAST178

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181. LUCA.
KOiK01921.
OMAiMIVESMI.
OrthoDBiPOG091H06GK.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4JVS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARSLFSPKN RELTEDEQQR LGLPVFVKPA RRGSSIGISK VDSWEAFAQA
60 70 80 90 100
VEIAFDHDNK MIVESMIHGR EVECGVLQYP EGSVIASAPA MLEGTEDGDE
110 120 130 140 150
GFYGFDAKYL DNTVTPSIPA PIGEEATAEV RRLAVRTFEA LNCEGLARVD
160 170 180 190 200
FFVTDNGEVI LNEINTLPGF TPISMYPQMF IAGGMEYPQL LDILIARALV

QD
Length:202
Mass (Da):22,234
Last modified:August 2, 2005 - v1
Checksum:i871FCE938EBEA690
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR931997 Genomic DNA. Translation: CAI37086.1.

Genome annotation databases

EnsemblBacteriaiCAI37086; CAI37086; jk0922.
KEGGicjk:jk0922.
PATRICi21512754. VBICorJei31838_0934.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR931997 Genomic DNA. Translation: CAI37086.1.

3D structure databases

ProteinModelPortaliQ4JVS1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi306537.jk0922.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI37086; CAI37086; jk0922.
KEGGicjk:jk0922.
PATRICi21512754. VBICorJei31838_0934.

Phylogenomic databases

eggNOGiCOG1181. LUCA.
KOiK01921.
OMAiMIVESMI.
OrthoDBiPOG091H06GK.

Enzyme and pathway databases

UniPathwayiUPA00219.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ4JVS1_CORJK
AccessioniPrimary (citable) accession number: Q4JVS1
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.