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Q4JVH4

- KGUA_CORJK

UniProt

Q4JVH4 - KGUA_CORJK

Protein

Guanylate kinase

Gene

gmk

Organism
Corynebacterium jeikeium (strain K411)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (02 Aug 2005)
      Previous versions | rss
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    Functioni

    Essential for recycling GMP and indirectly, cGMP.UniRule annotation

    Catalytic activityi

    ATP + GMP = ADP + GDP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 228ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCJEI306537:GJ8V-1054-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
    Alternative name(s):
    GMP kinaseUniRule annotation
    Gene namesi
    Name:gmkUniRule annotation
    Ordered Locus Names:jk1019
    OrganismiCorynebacterium jeikeium (strain K411)
    Taxonomic identifieri306537 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000000545: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 188188Guanylate kinasePRO_0000266311Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi306537.jk1019.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4JVH4.
    SMRiQ4JVH4. Positions 8-187.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – 188181Guanylate kinase-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.UniRule annotation
    Contains 1 guanylate kinase-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0194.
    HOGENOMiHOG000037640.
    KOiK00942.
    OMAiAGDLLEW.
    OrthoDBiEOG6CP410.

    Family and domain databases

    Gene3Di3.40.50.300. 3 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4JVH4-1 [UniParc]FASTAAdd to Basket

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    MSQDLNSGRI VVLAGPSAVG KSTVVRRLRT DVPDLFFSVS MTTRDPRPGE    50
    VDGEDYIYVT REQFEQNIAA DKMLEWAEIH GGLQLSGTPR EPIEKALAES 100
    RPVLVEVDLE GARNVKKMLP QVQTVFLAPP SWEELVDRLT GRGTETQDVI 150
    ERRLQTAKVE MASQSEFDHV VVNDDVDKAV AAISEILR 188
    Length:188
    Mass (Da):20,915
    Last modified:August 2, 2005 - v1
    Checksum:iFEBB9D9FF77683C6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR931997 Genomic DNA. Translation: CAI37183.1.
    RefSeqiWP_011273591.1. NC_007164.1.
    YP_250801.1. NC_007164.1.

    Genome annotation databases

    EnsemblBacteriaiCAI37183; CAI37183; jk1019.
    GeneIDi3433783.
    KEGGicjk:jk1019.
    PATRICi21512950. VBICorJei31838_1031.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR931997 Genomic DNA. Translation: CAI37183.1 .
    RefSeqi WP_011273591.1. NC_007164.1.
    YP_250801.1. NC_007164.1.

    3D structure databases

    ProteinModelPortali Q4JVH4.
    SMRi Q4JVH4. Positions 8-187.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 306537.jk1019.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAI37183 ; CAI37183 ; jk1019 .
    GeneIDi 3433783.
    KEGGi cjk:jk1019.
    PATRICi 21512950. VBICorJei31838_1031.

    Phylogenomic databases

    eggNOGi COG0194.
    HOGENOMi HOG000037640.
    KOi K00942.
    OMAi AGDLLEW.
    OrthoDBi EOG6CP410.

    Enzyme and pathway databases

    BioCyci CJEI306537:GJ8V-1054-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 3 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora."
      Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A.
      J. Bacteriol. 187:4671-4682(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K411.

    Entry informationi

    Entry nameiKGUA_CORJK
    AccessioniPrimary (citable) accession number: Q4JVH4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: August 2, 2005
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3