Q4JV42 (MQO_CORJK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	jk1151

Organism

Corynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]

Taxonomic identifier

306537 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 490	490	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000023797

Sequences

	Sequence		Length	Mass (Da)
	Q4JV42 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 5A8AB315A3CBEB74	FASTA	490	53,914
	10 20 30 40 50 60 MAHKDSVDVA LIGAGVISTT LSVMLKQLQP DWSQVIIERL DTPGAESSDP WNNAGTGHSA 70 80 90 100 110 120 LCELNYTPEV NGKIDISKAV GVNEKFQVSR QFWSYLVEQN VLGDPSEFIN KVPHVSFAQG 130 140 150 160 170 180 MDQVDYLKAR YEALKDHPLF PNMQYSDSDE KFAEFLPLMA RGRDFNNPVA ISWFDEGTDI 190 200 210 220 230 240 NYGALTRQYL DAVTAQGVEV RFGNEVKNIN RDGSKWKITT KNLHTGDTSM VTANFVFIGA 250 260 270 280 290 300 GGMALPLLQK AGIPEIKGYG GFPVSGQWLR CTNPELVEQH QAKVYGKASV GAPPMSVPHL 310 320 330 340 350 360 DTRVIDGKKG LLFGPYAGWT PKFLKKGSYL DLFKSLRVGN LPSYLGVGVQ EMGLTKYLIE 370 380 390 400 410 420 EVLKDQAARV ESLREYMPEA RAEDWELVTA GQRVQVIKPI GAPKFGSLEF GTALINSNDG 430 440 450 460 470 480 SIAGLMGASP GASIAPSAML EVLERCFGNR IADWAPKLRE MIPSYGTRLS KDANLFNEQW 490 DRSQKALKLV

References

[1]

"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora." Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A. J. Bacteriol. 187:4671-4682(2005) [PubMed: 15968079] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K411.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR931997 Genomic DNA. Translation: CAI37315.1.
RefSeq	YP_250933.1. NC_007164.1.
3D structure databases
ProteinModelPortal	Q4JV42.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4JV42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3432487.
GenomeReviews	Gene locus jk1151 in contig CR931997_GR.
KEGG	cjk:jk1151.
NMPDR	fig|306537.3.peg.1295.
PATRIC	21513230. VBICorJei31838_1164.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	REMIPSY.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	CJEI306537:JK1151-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_CORJK

Accession

Primary (citable) accession number: Q4JV42

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program