ID   COAA_CORJK              Reviewed;         308 AA.
AC   Q4JU68;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=Pantothenate kinase;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase;
GN   Name=coaA; OrderedLocusNames=jk1466;
OS   Corynebacterium jeikeium (strain K411).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=306537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15968079; DOI=10.1128/JB.187.13.4671-4682.2005;
RA   Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B.,
RA   Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T.,
RA   Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P.,
RA   Puehler A.;
RT   "Complete genome sequence and analysis of the multiresistant
RT   nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring
RT   bacterium of the human skin flora.";
RL   J. Bacteriol. 187:4671-4682(2005).
CC   -!- CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'-
CC       phosphopantothenate.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 1/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the prokaryotic pantothenate kinase family.
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DR   EMBL; CR931997; CAI37639.1; -; Genomic_DNA.
DR   RefSeq; YP_251257.1; -.
DR   GeneID; 3432188; -.
DR   GenomeReviews; CR931997_GR; jk1466.
DR   KEGG; cjk:jk1466; -.
DR   NMPDR; fig|306537.3.peg.606; -.
DR   HOGENOM; Q4JU68; -.
DR   OMA; Q4JU68; PKVDLIT.
DR   BioCyc; CJEI306537:JK1466-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00215; -; 1.
DR   InterPro; IPR004566; PanK_bact.
DR   InterPro; IPR006083; PRK_URK.
DR   PANTHER; PTHR10285:SF7; PanK_bact; 1.
DR   Pfam; PF00485; PRK; 1.
DR   PIRSF; PIRSF000545; Pantothenate_kin; 1.
DR   TIGRFAMs; TIGR00554; panK_bact; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    308       Pantothenate kinase.
FT                                /FTId=PRO_0000325549.
FT   NP_BIND      93    100       ATP (Potential).
SQ   SEQUENCE   308 AA;  35476 MW;  586DF57968A42BF7 CRC64;
     MDAMTSPSPY IELDRTQWRT LRKSMPQVLT EDELEQLRGI GDEIDLEEVS EVYLPLSRLI
     FLRVEAHRRL NAATETFLGE AMPQIPYIIG VCGSVAVGKS TTARVLQVLL QRWETNPRVD
     LVTTDGFLLP TAELERRKLM HRKGFPESYD QAELLSFITK VKSGTQKVQA PVYSHEAYDR
     IPDQTITVDR PDILIVEGLN VLQTGPTLMV SDLFDFSVYV DARREDIEDW YIDRFLRLKN
     TAFKDPEAHF HHFANFSDEE ATVVAREIWQ TVNLPNLMEN ILPTRVRASL VLRKGPDHLV
     QKVRMRKI
//