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Q4JU38 (PTH2_CORJK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase 2

Short name=PTH 2
EC=3.1.1.29
Gene names
Name:pth2
Ordered Locus Names:jk1496
OrganismCorynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]
Taxonomic identifier306537 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length240 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083

Subunit structure

Monomer By similarity. HAMAP MF_00083

Subcellular location

Cytoplasm By similarity HAMAP MF_00083.

Sequence similarities

Belongs to the PTH family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 240240Peptidyl-tRNA hydrolase 2 HAMAP MF_00083
PRO_0000264026

Sequences

Sequence LengthMass (Da)Tools
Q4JU38 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 5FACA1DD8B825B7C

FASTA24026,242
        10         20         30         40         50         60 
MAVSFLQSLF SVFRKKSSPQ EPATTTAGGP AKRTKLTVGE LQEFAPEWIV IGLGNPGAKY 

        70         80         90        100        110        120 
ADTRHNIGYW PIDRLVERYE AQWLPVEGQK AHAALITVEE TPVLLLRSTT YMNNSGEAVG 

       130        140        150        160        170        180 
PLASALSLPA ERIIVCHDEL DIAAGQVRIK DKGGEGGHNG LRSMTAELGT QHYVRVRMGI 

       190        200        210        220        230        240 
GRPPKGTSVI DFVLSPFEEA DIDAENGWME NTLRDSVDSV TLIVNNGTDI ARNDIHTRKH 

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References

[1]"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora."
Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A.
J. Bacteriol. 187:4671-4682(2005) [PubMed: 15968079] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K411.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR931997 Genomic DNA. Translation: CAI37669.1.
RefSeqYP_251287.1. NC_007164.1.

3D structure databases

ProteinModelPortalQ4JU38.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4JU38.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3432995.
GenomeReviewsGene locus jk1496 in contig CR931997_GR.
KEGGcjk:jk1496.
NMPDRfig|306537.3.peg.749.
PATRIC21513942. VBICorJei31838_1516.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0193.
HOGENOMHBG610927.
OMAPEWIVIG.
ProtClustDBPRK05426.

Enzyme and pathway databases

BioCycCJEI306537:JK1496-MONOMER.

Family and domain databases

HAMAPMF_00083. Pept_tRNA_hydro_bact.
[Tree]
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
Gene3DG3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KOK01056.
PANTHERPTHR17224. Pept_tRNA_hydro. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMsTIGR00447. Pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. False negative.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTH2_CORJK
AccessionPrimary (citable) accession number: Q4JU38
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: August 2, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families