Q4JTD7 (GLMM_CORJK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	jk1743

Organism

Corynebacterium jeikeium (strain K411) [Complete proteome] [HAMAP]

Taxonomic identifier

306537 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147880
Sites
	Active site	104	1	Phosphoserine intermediate By similarity
	Metal binding	104	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4JTD7 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 095EAC26B1D2FCD0	FASTA	447	46,357
	10 20 30 40 50 60 MGKLFGTDGV RGLANKKLTA PLAMKLGAAA ARVLVSKEEV GGRRPTAVVG RDPRVSGEML 70 80 90 100 110 120 TAALSAGMAS QGVDVLDVGV IPTPAVAFLT DDFGADMGVM ISASHNPMPD NGIKFFAAGG 130 140 150 160 170 180 RKLQDDVEDE IEATMLELPE TGPTGAAIGR ILDESSDALE RYLAHVGTAI NHPLDGIRVV 190 200 210 220 230 240 VDCANGAAST AAPEAYRQAG ADVVAIHSRP NSFNINDGVG STHIEVLQKA VLEHQADLGL 250 260 270 280 290 300 AHDGDADRCL AVDSEGNVVD GDQIMAILAV AMKENGELKQ NTLVATVMSN LGMKLAMRAN 310 320 330 340 350 360 GIKVLETQVG DRYVLAELLA SDLSLGGEQS GHVIISEHAT TGDGTLTGLT LMARMAQTGK 370 380 390 400 410 420 PLSELASVMT VLPQTLINVP VADKSVIADD ERVVEAIAKA EEDLGDAGRV LLRPSGTEEL 430 440 FRVMVEAADP GTARRIAGKL AAVVAEV

References

[1]

"Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora." Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A., Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F., Rupp O., Schneiker S., Viehoever P., Puehler A. J. Bacteriol. 187:4671-4682(2005) [PubMed: 15968079] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K411.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR931997 Genomic DNA. Translation: CAI37920.1.
RefSeq	YP_251538.1. NC_007164.1.
3D structure databases
ProteinModelPortal	Q4JTD7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4JTD7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3432591.
GenomeReviews	Gene locus jk1743 in contig CR931997_GR.
KEGG	cjk:jk1743.
NMPDR	fig|306537.3.peg.1682.
PATRIC	21514444. VBICorJei31838_1767.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	CJEI306537:JK1743-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CORJK

Accession

Primary (citable) accession number: Q4JTD7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	August 2, 2005
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program