Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q4JQI1 (COX3_TETNG) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:mt-co3
Synonyms:coiii, coxiii, mtco3
Encoded onMitochondrion
OrganismTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) [Reference proteome]
Taxonomic identifier99883 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiEuteleosteiNeoteleosteiAcanthomorphaAcanthopterygiiPercomorphaTetraodontiformesTetradontoideaTetraodontidaeTetraodon

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Cytochrome c oxidase subunit 3
PRO_0000183861

Regions

Transmembrane7 – 2721Helical; Potential
Transmembrane31 – 5121Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q4JQI1 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: DC27E03C9F452916

FASTA26129,726
        10         20         30         40         50         60 
MAHQAHAYHM VDPSPWPLTG AVAALLLTSG LAIWFPFNSL ILLTLGLVLL LLTMYQWWRD 

        70         80         90        100        110        120 
IVREGTFQGH HTPPVQKGLR YGMILFITSE VFFFLGFFWA FYHSSLAPTP ELGGCWPPTG 

       130        140        150        160        170        180 
IVPLNPFEVP LLNTAVLLAS GVTVTWAHHS IMEGERKQAI HSLTLTILLG FYFTFLQAME 

       190        200        210        220        230        240 
YYEAPFTIAD GVYGSTFFVA TGFHGLHVII GSTFLAICLL RQIRYHFTSE HHFGFEAAAW 

       250        260 
YWHFVDVVWL FLYISIYWWG S 

« Hide

References

[1]"The complete nucleotide sequence of the mitochondrial genome of Tetraodon nigroviridis."
Yue G.H., Lo L.C., Zhu Z.Y., Lin G., Feng F.
DNA Seq. 17:115-121(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ019313 Genomic DNA. Translation: AAY26162.1.
RefSeqYP_254667.1. NC_007176.1.

3D structure databases

ProteinModelPortalQ4JQI1.
SMRQ4JQI1. Positions 1-261.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSTNIT00000023289; ENSTNIP00000023047; ENSTNIG00000019783.
GeneID3453252.

Organism-specific databases

CTD4514.

Phylogenomic databases

eggNOGCOG1845.
GeneTreeENSGT00390000013064.
HOVERGENHBG016686.
OMAFFWAFYH.
OrthoDBEOG72VH70.
ProtClustDBMTH00130.
TreeFamTF343435.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_TETNG
AccessionPrimary (citable) accession number: Q4JQI1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: August 2, 2005
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families