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Protein
Submitted name:

11B-hydroxysteroid dehydrogenase type 1

Gene

Hsd11b1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
11B-hydroxysteroid dehydrogenase type 1Imported
Submitted name:
Hydroxysteroid 11-beta dehydrogenase 1Imported
Gene namesi
Name:Hsd11b1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103562 Hsd11b1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 21HelicalSequence analysisAdd BLAST16

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000016194

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1205 Eukaryota
COG1028 LUCA
HOGENOMiHOG000010276
HOVERGENiHBG005481
KOiK15680
OMAiIGREMAY
OrthoDBiEOG091G0H0R

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

Q4JHD9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVMKNYLLP ILVLFLAYYY YSTNEEFRPE MLQGKKVIVT GASKGIGREM
60 70 80 90 100
AYHLSKMGAH VVLTARSEEG LQKVVSRCLE LGAASAHYIA GTMEDMTFAE
110 120 130 140 150
QFIVKAGKLM GGLDMLILNH ITQTSLSLFH DDIHSVRRVM EVNFLSYVVM
160 170 180 190 200
STAALPMLKQ SNGSIAVISS LAGKMTQPMI APYSASKFAL DGFFSTIRTE
210 220 230 240 250
LYITKVNVSI TLCVLGLIDT ETAMKEISGI INAQASPKEE CALEIIKGTA
260 270 280 290
LRKSEVYYDK SPLTPILLGN PGRKIMEFFS LRYYNKDMFV SN
Length:292
Mass (Da):32,364
Last modified:August 2, 2005 - v1
Checksum:iADE42B11D82DD6CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132364 mRNA Translation: AAI32365.1
BC138780 mRNA Translation: AAI38781.1
BC145415 mRNA Translation: AAI45416.1
DQ089001 mRNA Translation: AAY98349.1
AK149518 mRNA Translation: BAE28932.1
RefSeqiNP_001038216.1, NM_001044751.1
NP_032314.2, NM_008288.2
UniGeneiMm.28328

Genome annotation databases

GeneIDi15483
KEGGimmu:15483

Similar proteinsi

Entry informationi

Entry nameiQ4JHD9_MOUSE
AccessioniPrimary (citable) accession number: Q4JHD9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)