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Protein

Pentaxin

Gene

Apcs

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 2 calcium ions per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
PentaxinUniRule annotation
Alternative name(s):
PentraxinUniRule annotation
Gene namesi
Name:ApcsImported
Synonyms:SapImported
ORF Names:mCG_1204Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98229 Apcs

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20UniRule annotationAdd BLAST20
ChainiPRO_501420585121 – 224PentaxinUniRule annotationAdd BLAST204

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi56 ↔ 115PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiQ4JFI8

Expressioni

Gene expression databases

BgeeiENSMUSG00000026542
ExpressionAtlasiQ4JFI8 baseline and differential

Interactioni

Subunit structurei

Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ4JFI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pentraxin family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J1FD Eukaryota
ENOG410YN8S LUCA
HOVERGENiHBG005405
OMAiFTLCFRA
OrthoDBiEOG091G0H6X

Family and domain databases

CDDicd00152 PTX, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR030476 Pentaxin_CS
IPR001759 Pentraxin-related
PfamiView protein in Pfam
PF00354 Pentaxin, 1 hit
PRINTSiPR00895 PENTAXIN
SMARTiView protein in SMART
SM00159 PTX, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS00289 PTX_1, 1 hit
PS51828 PTX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q4JFI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLLLWMFV FTSLLSEAFC QTDLKRKVFV FPRESETDHV KLIPHLEKPL
60 70 80 90 100
QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV
110 120 130 140 150
TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS
160 170 180 190 200
IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP
210 220
NILNWQALNY EINGYVVIRP RVWD
Length:224
Mass (Da):26,247
Last modified:August 2, 2005 - v1
Checksum:i1CDBC15F45E50DCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S40320 Genomic DNA Translation: AAY88178.1
HQ283363 Genomic DNA Translation: ADZ99751.1
AK144248 mRNA Translation: BAE25796.1
AK165699 mRNA Translation: BAE38344.1
CH466520 Genomic DNA Translation: EDL39002.1
RefSeqiNP_035448.2, NM_011318.2
UniGeneiMm.330510

Genome annotation databases

GeneIDi20219
KEGGimmu:20219

Similar proteinsi

Entry informationi

Entry nameiQ4JFI8_MOUSE
AccessioniPrimary (citable) accession number: Q4JFI8
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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