ID   NADM1_SULAC             Reviewed;         175 AA.
AC   Q4JBW3;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Nicotinamide-nucleotide adenylyltransferase 1;
DE            EC=2.7.7.1;
DE   AltName: Full=NAD(+) pyrophosphorylase 1;
DE   AltName: Full=NAD(+) diphosphorylase 1;
DE   AltName: Full=NMN adenylyltransferase 1;
GN   OrderedLocusNames=Saci_0300;
OS   Sulfolobus acidocaldarius.
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=2285;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770;
RX   PubMed=15995215; DOI=10.1128/JB.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- CATALYTIC ACTIVITY: ATP + nicotinamide ribonucleotide =
CC       diphosphate + NAD(+).
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from
CC       nicotinamide ribonucleotide: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the archaeal NMN adenylyltransferase
CC       family.
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DR   EMBL; CP000077; AAY79716.1; -; Genomic_DNA.
DR   RefSeq; YP_255009.1; -.
DR   GeneID; 3474564; -.
DR   GenomeReviews; CP000077_GR; Saci_0300.
DR   KEGG; sai:Saci_0300; -.
DR   NMPDR; fig|330779.3.peg.1065; -.
DR   HOGENOM; Q4JBW3; -.
DR   BioCyc; SACI330779:SACI_0300-MON; -.
DR   BRENDA; 2.7.7.1; 434.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase...; IEA:HAMAP.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00243; -; 1.
DR   InterPro; IPR004821; Cyt_trans_rel.
DR   InterPro; IPR004820; Cytidylyltransf.
DR   InterPro; IPR006418; NMN_Atrans_arc.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Gene3D; G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
DR   Pfam; PF01467; CTP_transf_2; 1.
DR   TIGRFAMs; TIGR01527; arch_NMN_Atrans; 1.
DR   TIGRFAMs; TIGR00125; cyt_tran_rel; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; NAD; Nucleotide-binding;
KW   Nucleotidyltransferase; Pyridine nucleotide biosynthesis; Transferase.
FT   CHAIN         1    175       Nicotinamide-nucleotide
FT                                adenylyltransferase 1.
FT                                /FTId=PRO_0000135003.
SQ   SEQUENCE   175 AA;  20492 MW;  2ED7253B37B390F2 CRC64;
     MRALFPGRFQ PFHLGHLQVV KWLLDRYEEL IIMIGSGQES HSPYNPFTAG ERLVMVKESL
     AETGIDLRKV VIFPVMESFT SKNWIRIVEM YSPHFDVIIS GNPLVYTVAK EAGYMVERVP
     MFNRDIYNAT RIRKLIMEND LKWMECVPKS VSQFIRDIKG DERIRDVTKN DYTED
//