Reviewed, UniProtKB/Swiss-Prot Q4JAT0 (NADM2_SULAC)

Names and origin

Protein names

Recommended name:
    Nicotinamide-nucleotide adenylyltransferase 2
    EC=2.7.7.1
Alternative name(s):
    NAD(+) pyrophosphorylase 2
    NAD(+) diphosphorylase 2
    NMN adenylyltransferase 2

Gene names

Ordered Locus Names:

Saci_0720

Organism

Sulfolobus acidocaldarius [Complete proteome] [HAMAP]

Taxonomic identifier

2285 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + nicotinamide ribonucleotide = diphosphate + NAD+. HAMAP MF_00243
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide ribonucleotide: step 1/1. HAMAP MF_00243
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the archaeal NMN adenylyltransferase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding NAD Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nicotinamide-nucleotide adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Nicotinamide-nucleotide adenylyltransferase 2 HAMAP MF_00243		PRO_0000135004

Sequences

	Sequence		Length	Mass (Da)
	Q4JAT0-1 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 399149E197E76C4E	FASTA	171	19,935
	10 20 30 40 50 60 MHRGLYPGRF QPFHIGHLEV VKWSMKHVDE LIIVIGSAQE SHTLSNPFTA GERIEMIRRT 70 80 90 100 110 120 LDKENLDLSK VYIIPIPDIM MNSVWVSHIK TFAPNFDVII SRNPLVNRLF KEANVEVLQP 130 140 150 160 170 PPFDRHKYNS TLIRRYIIEG NEEWKKLVPK SVLDYLLEIH GDERLRSIAG L

References

[1]

"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota." Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A. J. Bacteriol. 187:4992-4999(2005) [PubMed: 15995215] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000077 Genomic DNA. Translation: AAY80099.1.
RefSeq	YP_255392.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3472566.
GenomeReviews	Gene locus Saci_0720 in contig CP000077_GR.
KEGG	sai:Saci_0720.
NMPDR	fig|330779.3.peg.70.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4JAT0.
OMA	Q4JAT0. IGRFQPY.
Enzyme and pathway databases
BioCyc	SACI330779:SACI_0720-MON.
BRENDA	2.7.7.1. 434.
Family and domain databases
HAMAP	MF_00243. [Tree]
InterPro	IPR004821. Cyt_trans_rel. IPR004820. Cytidylyltransf. IPR006418. NMN_Atrans_arc. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01467. CTP_transf_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR01527. arch_NMN_Atrans. 1 hit. TIGR00125. cyt_tran_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NADM2_SULAC

Accession

Primary (citable) accession number: Q4JAT0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 27, 2005
Last sequence update:	August 2, 2005
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)