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Protein

DNA polymerase sliding clamp 1

Gene

pcn1

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clamp 1UniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homolog 1UniRule annotation
Short name:
PCNA 1UniRule annotation
Gene namesi
Name:pcn1UniRule annotation
Ordered Locus Names:Saci_0826
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001018 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001492101 – 247DNA polymerase sliding clamp 1Add BLAST247

Proteomic databases

PRIDEiQ4JAI6

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi330779.Saci_0826

Structurei

3D structure databases

ProteinModelPortaliQ4JAI6
SMRiQ4JAI6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
TIGRFAMsiTIGR00590 pcna, 1 hit
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q4JAI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIVYDDVRD LKNIVETLTK FIDEGLFEIG QDGIRLVAVD KAHVSLINIE
60 70 80 90 100
LYKELFKEYE VEDEFKFGFN SQYLAKILSI AKRKEEISIE SDSPERVKIT
110 120 130 140 150
LGGALNRVFI INNIQVSPPE VPEVNLEFEV KASLSSKAFK TTINEISAVT
160 170 180 190 200
DTVDIIAVED KVILKGEGKE GSQIENEFSK DTGAISDMEF KNEAKSPYDV
210 220 230 240
NYLSDILSLT NLSDYTRLAF STEKPLELEF NMEGGGKVTY LLAPKLS
Length:247
Mass (Da):27,765
Last modified:September 27, 2005 - v2
Checksum:i57ECBC8A86CD172C
GO

Sequence cautioni

The sequence AAY80192 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000077 Genomic DNA Translation: AAY80192.1 Different initiation.

Genome annotation databases

EnsemblBacteriaiAAY80192; AAY80192; Saci_0826
KEGGisai:Saci_0826
PATRICifig|330779.12.peg.790

Similar proteinsi

Entry informationi

Entry nameiPCNA1_SULAC
AccessioniPrimary (citable) accession number: Q4JAI6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: September 27, 2005
Last modified: May 23, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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