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Q4J929 (OGG1_SULAC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable N-glycosylase/DNA lyase

Including the following 2 domains:

  1. 8-oxoguanine DNA glycosylase
    EC=3.2.2.-
  2. DNA-(apurinic or apyrimidinic site) lyase
    Short name=AP lyase
    EC=4.2.99.18
Gene names
Name:ogg
Ordered Locus Names:Saci_1367
OrganismSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) [Complete proteome] [HAMAP]
Taxonomic identifier330779 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) By similarity. HAMAP-Rule MF_00241

Catalytic activity

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. HAMAP-Rule MF_00241

Sequence similarities

Belongs to the type-2 OGG1 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Probable N-glycosylase/DNA lyase HAMAP-Rule MF_00241
PRO_0000159565

Sites

Active site1281 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4J929 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 28AF6E867FC8D207

FASTA20323,869
        10         20         30         40         50         60 
MLRSLVLNEK LRARVLERAE EFLLNNKADE EVWFRELVLC ILTSNSSFIS AYKSMNYILD 

        70         80         90        100        110        120 
KILYMDEKEI SILLQESGYR FYNLKAKYLY RAKNLYGKVK KTIKEIADKD QMQAREFIAT 

       130        140        150        160        170        180 
HIYGIGYKEA SHFLRNVGYL DLAIIDRHIL RFINNLGIPI KLKSKREYLL AESLLRSIAN 

       190        200 
NLNVQVGLLD LFIFFKQTNT IVK 

« Hide

References

[1]"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota."
Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.
J. Bacteriol. 187:4992-4999(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000077 Genomic DNA. Translation: AAY80701.1.
RefSeqYP_255994.1. NC_007181.1.

3D structure databases

ProteinModelPortalQ4J929.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING330779.Saci_1367.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY80701; AAY80701; Saci_1367.
GeneID3472932.
KEGGsai:Saci_1367.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1059.
HOGENOMHOG000224507.
KOK03653.
OMAELCFCIL.
ProtClustDBPRK01229.

Enzyme and pathway databases

BioCycSACI330779:GH9J-1345-MONOMER.

Family and domain databases

Gene3D1.10.340.30. 1 hit.
HAMAPMF_00241. Ogg.
InterProIPR012092. DNA_glyclase/DNA_lyase_thermo.
IPR011257. DNA_glycosylase.
IPR003265. HhH-GPD_domain.
[Graphical view]
PfamPF00730. HhH-GPD. 1 hit.
[Graphical view]
PIRSFPIRSF005954. Thrmst_ogg. 1 hit.
SMARTSM00478. ENDO3c. 1 hit.
[Graphical view]
SUPFAMSSF48150. SSF48150. 1 hit.
ProtoNetSearch...

Entry information

Entry nameOGG1_SULAC
AccessionPrimary (citable) accession number: Q4J929
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: August 2, 2005
Last modified: February 19, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families