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Q4J904

- SYR_SULAC

UniProt

Q4J904 - SYR_SULAC

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSACI330779:GH9J-1374-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Saci_1396
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001018: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 618618Arginine--tRNA ligasePRO_0000151655Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi330779.Saci_1396.

Structurei

3D structure databases

ProteinModelPortaliQ4J904.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi113 – 12311"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
KOiK01887.
OMAiAGEWDAT.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4J904-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNPIRSVKEE FCEIVANGLG ISKDVIFKTL EYPPREELGD ISLPLPSLKL
60 70 80 90 100
NVRTEVTFSH GKLIKEVRKT GIYVNAFVDE KELFKLLFTE MQDDYGVEKT
110 120 130 140 150
ENPKRIVVEH TSANPIHPLH IGHLRNSILG DTISRMLKIR GHDVNRRFYV
160 170 180 190 200
NDAGRQVAIL TLGYILLGEP EPSPKVDHWF GLIYSITNVI IEIRELKEEL
210 220 230 240 250
KKDLDPDTYK DKINRLDELV ATAQSLRERN PEFFDKLADA INSIPDVESE
260 270 280 290 300
IQKIIKSYEK GDDPKIKQIV RKIVNLNLDG FRESLDKLEI SFDVYDYESE
310 320 330 340 350
LLWSGMVDEI LSKAFQIAKD YKGTKALELE DINEKIKEIL NIPKGLKLPP
360 370 380 390 400
LVLTRSDGTS LYTTRDIAYT VKKFSDFKAD TVINVIAEQQ SIPQMQLRAS
410 420 430 440 450
LYLLGYERLA QNLVHYSYGM VNLQGMRMSG RLGRFISLDD VIEKVSEVAK
460 470 480 490 500
KKIEEKSGDI TNLRDIVNSA IRYAILSVAS NKPVTFNINN IVDFEQNSGP
510 520 530 540 550
YLQYTYARAY NILAKNQDEI KLTDADLSDL IGDKRRLLLL IARFPETFNK
560 570 580 590 600
AIDELRPEDL IDFLRRTADV FNRWYNFERV LQEPDYRKRI TRLFIVKGIE
610
RVLYNGLNAL GIKPLSKM
Length:618
Mass (Da):71,087
Last modified:August 2, 2005 - v1
Checksum:i11C9ACB100739ABA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000077 Genomic DNA. Translation: AAY80726.1.
RefSeqiYP_256019.1. NC_007181.1.

Genome annotation databases

EnsemblBacteriaiAAY80726; AAY80726; Saci_1396.
GeneIDi3473399.
KEGGisai:Saci_1396.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000077 Genomic DNA. Translation: AAY80726.1 .
RefSeqi YP_256019.1. NC_007181.1.

3D structure databases

ProteinModelPortali Q4J904.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 330779.Saci_1396.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY80726 ; AAY80726 ; Saci_1396 .
GeneIDi 3473399.
KEGGi sai:Saci_1396.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247213.
KOi K01887.
OMAi AGEWDAT.

Enzyme and pathway databases

BioCyci SACI330779:GH9J-1374-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota."
    Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.
    J. Bacteriol. 187:4992-4999(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.

Entry informationi

Entry nameiSYR_SULAC
AccessioniPrimary (citable) accession number: Q4J904
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: August 2, 2005
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3