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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Saci_1396
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001018 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516551 – 618Arginine--tRNA ligaseAdd BLAST618

Interactioni

Protein-protein interaction databases

STRINGi330779.Saci_1396.

Structurei

3D structure databases

ProteinModelPortaliQ4J904.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 123"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487. Archaea.
COG0018. LUCA.
HOGENOMiHOG000247213.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG093Z013U.

Family and domain databases

Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001278. Arg-tRNA-ligase.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4J904-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIRSVKEE FCEIVANGLG ISKDVIFKTL EYPPREELGD ISLPLPSLKL
60 70 80 90 100
NVRTEVTFSH GKLIKEVRKT GIYVNAFVDE KELFKLLFTE MQDDYGVEKT
110 120 130 140 150
ENPKRIVVEH TSANPIHPLH IGHLRNSILG DTISRMLKIR GHDVNRRFYV
160 170 180 190 200
NDAGRQVAIL TLGYILLGEP EPSPKVDHWF GLIYSITNVI IEIRELKEEL
210 220 230 240 250
KKDLDPDTYK DKINRLDELV ATAQSLRERN PEFFDKLADA INSIPDVESE
260 270 280 290 300
IQKIIKSYEK GDDPKIKQIV RKIVNLNLDG FRESLDKLEI SFDVYDYESE
310 320 330 340 350
LLWSGMVDEI LSKAFQIAKD YKGTKALELE DINEKIKEIL NIPKGLKLPP
360 370 380 390 400
LVLTRSDGTS LYTTRDIAYT VKKFSDFKAD TVINVIAEQQ SIPQMQLRAS
410 420 430 440 450
LYLLGYERLA QNLVHYSYGM VNLQGMRMSG RLGRFISLDD VIEKVSEVAK
460 470 480 490 500
KKIEEKSGDI TNLRDIVNSA IRYAILSVAS NKPVTFNINN IVDFEQNSGP
510 520 530 540 550
YLQYTYARAY NILAKNQDEI KLTDADLSDL IGDKRRLLLL IARFPETFNK
560 570 580 590 600
AIDELRPEDL IDFLRRTADV FNRWYNFERV LQEPDYRKRI TRLFIVKGIE
610
RVLYNGLNAL GIKPLSKM
Length:618
Mass (Da):71,087
Last modified:August 2, 2005 - v1
Checksum:i11C9ACB100739ABA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000077 Genomic DNA. Translation: AAY80726.1.
RefSeqiWP_011278228.1. NC_007181.1.

Genome annotation databases

EnsemblBacteriaiAAY80726; AAY80726; Saci_1396.
GeneIDi3473399.
KEGGisai:Saci_1396.
PATRICifig|330779.12.peg.1345.

Similar proteinsi

Entry informationi

Entry nameiSYR_SULAC
AccessioniPrimary (citable) accession number: Q4J904
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: August 2, 2005
Last modified: November 22, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families