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Q4J904 (SYR_SULAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Saci_1396
OrganismSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) [Complete proteome] [HAMAP]
Taxonomic identifier330779 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length618 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 618618Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151655

Regions

Motif113 – 12311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q4J904 [UniParc].

Last modified August 2, 2005. Version 1.
Checksum: 11C9ACB100739ABA

FASTA61871,087
        10         20         30         40         50         60 
MNPIRSVKEE FCEIVANGLG ISKDVIFKTL EYPPREELGD ISLPLPSLKL NVRTEVTFSH 

        70         80         90        100        110        120 
GKLIKEVRKT GIYVNAFVDE KELFKLLFTE MQDDYGVEKT ENPKRIVVEH TSANPIHPLH 

       130        140        150        160        170        180 
IGHLRNSILG DTISRMLKIR GHDVNRRFYV NDAGRQVAIL TLGYILLGEP EPSPKVDHWF 

       190        200        210        220        230        240 
GLIYSITNVI IEIRELKEEL KKDLDPDTYK DKINRLDELV ATAQSLRERN PEFFDKLADA 

       250        260        270        280        290        300 
INSIPDVESE IQKIIKSYEK GDDPKIKQIV RKIVNLNLDG FRESLDKLEI SFDVYDYESE 

       310        320        330        340        350        360 
LLWSGMVDEI LSKAFQIAKD YKGTKALELE DINEKIKEIL NIPKGLKLPP LVLTRSDGTS 

       370        380        390        400        410        420 
LYTTRDIAYT VKKFSDFKAD TVINVIAEQQ SIPQMQLRAS LYLLGYERLA QNLVHYSYGM 

       430        440        450        460        470        480 
VNLQGMRMSG RLGRFISLDD VIEKVSEVAK KKIEEKSGDI TNLRDIVNSA IRYAILSVAS 

       490        500        510        520        530        540 
NKPVTFNINN IVDFEQNSGP YLQYTYARAY NILAKNQDEI KLTDADLSDL IGDKRRLLLL 

       550        560        570        580        590        600 
IARFPETFNK AIDELRPEDL IDFLRRTADV FNRWYNFERV LQEPDYRKRI TRLFIVKGIE 

       610 
RVLYNGLNAL GIKPLSKM 

« Hide

References

[1]"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota."
Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.
J. Bacteriol. 187:4992-4999(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000077 Genomic DNA. Translation: AAY80726.1.
RefSeqYP_256019.1. NC_007181.1.

3D structure databases

ProteinModelPortalQ4J904.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING330779.Saci_1396.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY80726; AAY80726; Saci_1396.
GeneID3473399.
KEGGsai:Saci_1396.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMAAGEWDAT.

Enzyme and pathway databases

BioCycSACI330779:GH9J-1374-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_SULAC
AccessionPrimary (citable) accession number: Q4J904
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: August 2, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries