Reviewed, UniProtKB/Swiss-Prot Q4J8P4 (PGP_SULAC)

Names and origin

Protein names

Recommended name:
    Phosphoglycolate phosphatase
      Short name=PGPase
      Short name=PGP
    EC=3.1.3.18

Gene names

Ordered Locus Names:

Saci_1518

Organism

Sulfolobus acidocaldarius [Complete proteome] [HAMAP]

Taxonomic identifier

2285 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the dephosphorylation of 2-phosphoglycolate By similarity.
Catalytic activity	2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_01419
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the archaeal SPP-like hydrolase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycolate phosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 227	227	Phosphoglycolate phosphatase HAMAP MF_01419		PRO_0000146727
Sites
	Active site	8	1	Nucleophile By similarity
	Metal binding	8	1	Magnesium By similarity
	Metal binding	10	1	Magnesium By similarity
	Metal binding	173	1	Magnesium By similarity
	Metal binding	177	1	Magnesium By similarity
	Binding site	150	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4J8P4-1 [UniParc]. Last modified August 2, 2005. Version 1. Checksum: 03CAD324863C5D55	FASTA	227	25,468
	10 20 30 40 50 60 MIRLILTDVD GTLTFDRDTY NIDLDAVDLL RKVEKKGIKV GLVSGNSYPV LRALYTYFGF 70 80 90 100 110 120 NGGIVAENGC IVYYDNQLKE VCERVERSLI SEFENRFGVK GSWQNQFKVC DFSFYPPILK 130 140 150 160 170 180 DEMVKWALDK GLYIKTSGYA VHISKSKRGK AEGVRELIKM HGLDKAEVVG IGDSSTDIEF 190 200 210 220 LEEVGIRVVV GNADESLKSI GDFVMREKSG KAVVEFIKKV ITGEINE

References

[1]

"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota." Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A. J. Bacteriol. 187:4992-4999(2005) [PubMed: 15995215] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000077 Genomic DNA. Translation: AAY80837.1.
RefSeq	YP_256130.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3474642.
GenomeReviews	Gene locus Saci_1518 in contig CP000077_GR.
KEGG	sai:Saci_1518.
NMPDR	fig|330779.3.peg.178.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4J8P4.
OMA	Q4J8P4. NKCRKYD.
Enzyme and pathway databases
BioCyc	SACI330779:SACI_1518-MON.
BRENDA	3.1.3.18. 434.
Family and domain databases
HAMAP	MF_01419. [Tree]
InterPro	IPR013200. HAD-SF_hydro-like_3. IPR006379. HAD-SF_hydro_IIB. IPR006382. SPPlik_hydro_arc. [Graphical view]
Pfam	PF08282. Hydrolase_3. 2 hits. [Graphical view]
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01487. SPP-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PGP_SULAC

Accession

Primary (citable) accession number: Q4J8P4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 27, 2005
Last sequence update:	August 2, 2005
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)