ID   GLPK2_SULAC             Reviewed;         497 AA.
AC   Q4J7A3;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=Glycerol kinase 2;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase 2;
DE   AltName: Full=Glycerokinase 2;
DE            Short=GK 2;
GN   Name=glpK2; OrderedLocusNames=Saci_2033;
OS   Sulfolobus acidocaldarius.
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=2285;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770;
RX   PubMed=15995215; DOI=10.1128/JB.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC       metabolism.
CC   -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC       phosphate.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; CP000077; AAY81329.1; -; Genomic_DNA.
DR   RefSeq; YP_256622.1; -.
DR   GeneID; 3474450; -.
DR   GenomeReviews; CP000077_GR; Saci_2033.
DR   KEGG; sai:Saci_2033; -.
DR   NMPDR; fig|330779.3.peg.1719; -.
DR   HOGENOM; Q4J7A3; -.
DR   OMA; Q4J7A3; ILESMAY.
DR   BioCyc; SACI330779:SACI_2033-MON; -.
DR   BRENDA; 2.7.1.30; 434.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00186; -; 1.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   PANTHER; PTHR10196:SF9; Glycerol_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    497       Glycerol kinase 2.
FT                                /FTId=PRO_0000059532.
FT   NP_BIND     406    410       ATP (By similarity).
FT   BINDING      13     13       Substrate (By similarity).
FT   BINDING      17     17       ATP (By similarity).
FT   BINDING      83     83       Substrate (By similarity).
FT   BINDING     134    134       Substrate (By similarity).
FT   BINDING     241    241       Substrate (By similarity).
FT   BINDING     263    263       ATP (By similarity).
FT   BINDING     305    305       ATP; via carbonyl oxygen (By similarity).
SQ   SEQUENCE   497 AA;  55356 MW;  8AEF78EEEF675CEB CRC64;
     MAEKYVIAID EGTTSARAIV FDKELNILGI GQNEFTQYYP QPGYVEHSPE EIWQAQLLAI
     NKALEKAKID RNNILSIGIT NQRETTVMWD TRTGKPIYNA IVWQDRRTAP ITDYLKANYL
     RLIKDRTGLV PDPYFSASKI KWILDNIPNA REKAEKGEIK FGTIDTYLIW KLTNGKAHVT
     DYSNASRTML FNIRKLEWDR EILEILNIPE AILPDVKPSS EIYGYAEILN SSIPISGDAG
     DQQAALFGQI AFNQGDVKCT YGTGSFILLN TGSNLVSSND LLTTIAWGVG KGITYALEGS
     IFITGAAVQW FRDGLRAIDV SDEIEPLAGS VPDNGGVYFV PAFTGLGAPY WDPYARGLII
     GITRGTTKAH IARAILESMA YQTMDVLGIM QRDSGIKIDA LKVDGGASKN DLLMQFQADI
     LKMKVVRPKI METTSMGVAM LAGLSVGYWN SMDELKQKWK IDQVFEPKMD DEYREKLYSG
     WKEAVRRALG WAKTIGG
//