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Protein
Submitted name:

Plasma membrane Ca(2+)-ATPase isoform 2

Gene

PMCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Plasma membrane Ca(2+)-ATPase isoform 2Imported
Gene namesi
Name:PMCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25108.

PTM / Processingi

Proteomic databases

PaxDbiQ4J699.
PeptideAtlasiQ4J699.

Expressioni

Gene expression databases

BgeeiENSG00000157087.
GenevisibleiQ4J699. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000324172.

Structurei

3D structure databases

ProteinModelPortaliQ4J699.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini47 – 12377Cation_ATPase_NInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0204. Eukaryota.
ENOG410XNNC. LUCA.
HOGENOMiHOG000265623.
HOVERGENiHBG061286.
KOiK05850.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01494. ATPase_P-type. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q4J699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDMTNSDFY SKNQRNESSH GGEFGCTMEE LRSLMELRGT EAVVKIKETY
60 70 80 90 100
GDTEAICRRL KTSPVEGLPG TAPDLEKRKQ IFGQNFIPPK KPKTFLQLVW
110 120 130 140 150
EALQDVTLII LEIAAIISLG LSFYHPPGEG NEGCATAQGG AEDEGEAEAG
160 170 180 190 200
WIEGAAILLS VICVVLVTAF NDWSKEKQFR GLQSRIEQEQ KFTVVRAGQV
210 220 230 240 250
VQIPVAEIVV GDIAQVKYGD LLPADGLFIQ GNDLKIDESS LTGESDQVRK
260 270 280 290 300
SVDKDPMLLS GTHVMEGSGR MLVTAVGVNS QTGIIFTLLG AGGEEEEKKD
310 320 330 340 350
KKGVKKGDGL QLPAADGAAA SNAADSANAS LVNGKMQDGN VDASQSKAKQ
360 370 380 390
QDGAAAMEMQ PLKSAEGGDA DDRKKASMHK KEKSVLQGKL TKL
Length:393
Mass (Da):42,028
Last modified:August 2, 2005 - v1
Checksum:iF192F2C4292D447C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei393 – 3931Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S95738 mRNA. Translation: AAA08378.1.
RefSeqiNP_001001331.1. NM_001001331.2.
UniGeneiHs.268942.

Genome annotation databases

GeneIDi491.
KEGGihsa:491.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S95738 mRNA. Translation: AAA08378.1.
RefSeqiNP_001001331.1. NM_001001331.2.
UniGeneiHs.268942.

3D structure databases

ProteinModelPortaliQ4J699.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000324172.

Proteomic databases

PaxDbiQ4J699.
PeptideAtlasiQ4J699.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi491.
KEGGihsa:491.

Organism-specific databases

CTDi491.
PharmGKBiPA25108.

Phylogenomic databases

eggNOGiKOG0204. Eukaryota.
ENOG410XNNC. LUCA.
HOGENOMiHOG000265623.
HOVERGENiHBG061286.
KOiK05850.

Miscellaneous databases

ChiTaRSiATP2B2. human.
GenomeRNAii491.

Gene expression databases

BgeeiENSG00000157087.
GenevisibleiQ4J699. HS.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01494. ATPase_P-type. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ4J699_HUMAN
AccessioniPrimary (citable) accession number: Q4J699
Entry historyi
Integrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.