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Protein
Submitted name:

Plasma membrane Ca(2+)-ATPase isoform 2

Gene

PMCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Plasma membrane Ca(2+)-ATPase isoform 2Imported
Gene namesi
Name:PMCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25108.

PTM / Processingi

Proteomic databases

PaxDbiQ4J699.
PeptideAtlasiQ4J699.

Expressioni

Gene expression databases

GenevisibleiQ4J699. HS.

Structurei

3D structure databases

ProteinModelPortaliQ4J699.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 123Cation_ATPase_NInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0204. Eukaryota.
ENOG410XNNC. LUCA.
HOGENOMiHOG000265623.
HOVERGENiHBG061286.
KOiK05850.

Family and domain databases

InterProiView protein in InterPro
IPR030322. ATP2B2.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR001757. P_typ_ATPase.
PANTHERiPTHR24093:SF377. PTHR24093:SF377. 1 hit.
PfamiView protein in Pfam
PF00690. Cation_ATPase_N. 1 hit.
SMARTiView protein in SMART
SM00831. Cation_ATPase_N. 1 hit.
SUPFAMiSSF81653. SSF81653. 1 hit.
SSF81665. SSF81665. 2 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q4J699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDMTNSDFY SKNQRNESSH GGEFGCTMEE LRSLMELRGT EAVVKIKETY
60 70 80 90 100
GDTEAICRRL KTSPVEGLPG TAPDLEKRKQ IFGQNFIPPK KPKTFLQLVW
110 120 130 140 150
EALQDVTLII LEIAAIISLG LSFYHPPGEG NEGCATAQGG AEDEGEAEAG
160 170 180 190 200
WIEGAAILLS VICVVLVTAF NDWSKEKQFR GLQSRIEQEQ KFTVVRAGQV
210 220 230 240 250
VQIPVAEIVV GDIAQVKYGD LLPADGLFIQ GNDLKIDESS LTGESDQVRK
260 270 280 290 300
SVDKDPMLLS GTHVMEGSGR MLVTAVGVNS QTGIIFTLLG AGGEEEEKKD
310 320 330 340 350
KKGVKKGDGL QLPAADGAAA SNAADSANAS LVNGKMQDGN VDASQSKAKQ
360 370 380 390
QDGAAAMEMQ PLKSAEGGDA DDRKKASMHK KEKSVLQGKL TKL
Length:393
Mass (Da):42,028
Last modified:August 2, 2005 - v1
Checksum:iF192F2C4292D447C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei393Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S95738 mRNA. Translation: AAA08378.1.
UniGeneiHs.268942.

Genome annotation databases

KEGGihsa:491.

Similar proteinsi

Entry informationi

Entry nameiQ4J699_HUMAN
AccessioniPrimary (citable) accession number: Q4J699
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: November 22, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.