ID   TRM10_GIBZE             Reviewed;         407 AA.
AC   Q4I8X0;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=tRNA (guanine-N(1)-)-methyltransferase;
DE            EC=2.1.1.31;
DE   AltName: Full=tRNA methyltransferase 10;
GN   Name=TRM10; ORFNames=FG06338;
OS   Gibberella zeae (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
OC   Gibberella.
OX   NCBI_TaxID=5518;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PH-1 / NRRL 31084;
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G.,
RA   Di Pietro A., Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G.,
RA   Antoniw J., Baldwin T., Calvo S.E., Chang Y.-L., DeCaprio D.,
RA   Gale L.R., Gnerre S., Goswami R.S., Hammond-Kosack K., Harris L.J.,
RA   Hilburn K., Kennell J.C., Kroken S., Magnuson J.K., Mannhaupt G.,
RA   Mauceli E.W., Mewes H.-W., Mitterbauer R., Muehlbauer G.,
RA   Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T., Qi W.,
RA   Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
CC   -!- FUNCTION: Catalyzes the formation of N(1)-methylguanine at
CC       position 9 (m1G9) in cytoplasmic tRNAs (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-
CC       homocysteine + tRNA containing N(1)-methylguanine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase trmD family.
CC       TRM10 subfamily.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AACM01000254; EAA74955.1; -; Genomic_DNA.
DR   RefSeq; XP_386514.1; -.
DR   GeneID; 2786641; -.
DR   KEGG; fgr:FG06338.1; -.
DR   BRENDA; 2.1.1.31; 74326.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0009019; F:tRNA (guanine-N1-)-methyltransferase activity; IEA:EC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR016009; tRNA_m1G_MeTrfase.
DR   InterPro; IPR007356; tRNA_m1G_MeTrfase_euk.
DR   PANTHER; PTHR13563; DUF425; 1.
DR   Pfam; PF01746; tRNA_m1G_MT; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Nucleus; S-adenosyl-L-methionine;
KW   Transferase; tRNA processing.
FT   CHAIN         1    407       tRNA (guanine-N(1)-)-methyltransferase.
FT                                /FTId=PRO_0000060516.
SQ   SEQUENCE   407 AA;  46769 MW;  30151BC819DC5C24 CRC64;
     MDLDPAHKPS QAEETKEQGN EQGQVEQNQA QQDPTTGPQA ETEKAIIPSQ GSTIPQKRSA
     EDEPAQPMSK NALKRLRKQQ QWEAGKEDRK LKRKDSRIAR KVRKREERDA LIAQGINPYA
     NKQKPPSVNV PISLIFDCEF EQYMREKEII SLGSQITRSY SENKNAKYRT NIYVSNWNGK
     LAERFHQILD DKHQNWKGID FVEGDFIECA EKAREKMKHE NMIEPLQRSL TEKSPWARDE
     KDPLPLPDPE PEPRPEYSDI VYLSSDSPYT LERLEPNTSY VIGGLVDKNR EKGLCYKRAR
     ERGIRTARLP IGQYMVMQSR TVLTTNHVVE IMLKWLEYEN WGEAFMSVIP KRKGGKLKEQ
     QGASGETQET EEAEAEDPEE ENEETKDPDA EASASKQNTP KVEVTSK
//