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Q4H3L3

- Q4H3L3_CIOIN

UniProt

Q4H3L3 - Q4H3L3_CIOIN

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Protein
Submitted name: Mitogen-activated protein kinase
Gene
Ci-ERK5
Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinaseImported
Gene namesi
Name:Ci-ERK5Imported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000019973.

Structurei

3D structure databases

ProteinModelPortaliQ4H3L3.
SMRiQ4H3L3. Positions 31-350.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000113595.
HOVERGENiHBG108137.
InParanoidiQ4H3L3.
KOiK04464.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4H3L3-1 [UniParc]FASTAAdd to Basket

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MAESEPQKVL IKSKLSRKLG VQHQASDGFV LFDVGPQYKI LETIGTGAYG    50
IVCSAIDNKT GKHVAIKKVV QAFEVVTTAK RTLRELKLLL HFKHDNIVGI 100
KSIIQSKKED FKHVYFVMDL MESDLHHIIR SDQPLTTEHI CYFMYQLLRG 150
LKYIHSANVI HRDLKPSNLL VNENCELRIG DFGMARAVSQ EPEDHKSFMT 200
EYVATRWYRA PELMLSFGRY SQAIDMWSVG CIFAEMIGRR QIFPGKHYVH 250
QLQLIISVLG SPPSGLVSTI RSDRVRNYVT GLPSKSATPF KQLYTKATQP 300
MVDLLTSLLR FNPEERPTSV QALTHPFLSG YHDKDDEPTC HAPFDFQFEA 350
TATREGVHEE VTAVIKKYHE KKNRFAKQLT PIRRSEKTDP PKNDLLIFKK 400
PAAPVSFPKE SAPDAASTMD LDAGEAEAEK RPMITVQVLQ DEPVKDTKGA 450
AKKKTISEDT KLKIRDIIFA SMFAKQKGLG KPLDKVKKSV TAADRQKERE 500
SKRKKRLDRA AEKERKRREE TKNLLSEADR SLLDRWTKMQ KSTTTENPAK 550
QTETEEPKVT LIRHQSLPPS SIRQARQRQL IEATNVRPNS VHIDDATWLV 600
PSLDARLAPE TPMLQPSTDH PTVAPNTSMV PNTSWGTNCT ENTQQKQVEV 650
KRPSSLSVQP SNQDLTNQTL TRSDTEGLTA ISPGTVDRVL TQQFHVNHDL 700
HNPPQELEGA KQKEAARTPE LAGRLNVSNH GEFPSLGAIG YGLGVDISDI 750
IPQSAGDVAP GTSQELMTSA ASEQCSSSLL AEWSDLHRMH PQDMEALQRE 800
LELGSPMIVQ YET 813
Length:813
Mass (Da):91,346
Last modified:August 30, 2005 - v1
Checksum:i8C901CE22F8D6EF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB210409 mRNA. Translation: BAE06414.1.
RefSeqiNP_001071698.1. NM_001078230.1.
UniGeneiCin.30537.

Genome annotation databases

GeneIDi778597.
KEGGicin:778597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB210409 mRNA. Translation: BAE06414.1 .
RefSeqi NP_001071698.1. NM_001078230.1.
UniGenei Cin.30537.

3D structure databases

ProteinModelPortali Q4H3L3.
SMRi Q4H3L3. Positions 31-350.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7719.ENSCINP00000019973.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 778597.
KEGGi cin:778597.

Organism-specific databases

CTDi 778597.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000113595.
HOVERGENi HBG108137.
InParanoidi Q4H3L3.
KOi K04464.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomewide surveys of developmentally relevant genes in Ciona intestinalis."
    Satou Y., Satoh N.
    Dev. Genes Evol. 213:211-212(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks."
    Imai K.S., Hino K., Yagi K., Satoh N., Satou Y.
    Development 131:4047-4058(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Expressed genes in Ciona intestinalis."
    Satou Y.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ4H3L3_CIOIN
AccessioniPrimary (citable) accession number: Q4H3L3
Entry historyi
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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