Q4H3L3 (Q4H3L3_CIOIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitogen-activated protein kinase EMBL BAE06414.1

Gene names

Name:

Ci-ERK5 EMBL BAE06414.1

Organism

Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) EMBL BAE06414.1

Taxonomic identifier

7719 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona

Protein attributes

Sequence length	813 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS003527
Sequence similarities	Contains 1 protein kinase domain. SAAS SAAS003527

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 SAAS SAAS003527 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS003527 Transferase
Gene Ontology (GO)
Biological_process	MAPK cascade Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW MAP kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4H3L3 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: 8C901CE22F8D6EF6	FASTA	813	91,346
	10 20 30 40 50 60 MAESEPQKVL IKSKLSRKLG VQHQASDGFV LFDVGPQYKI LETIGTGAYG IVCSAIDNKT 70 80 90 100 110 120 GKHVAIKKVV QAFEVVTTAK RTLRELKLLL HFKHDNIVGI KSIIQSKKED FKHVYFVMDL 130 140 150 160 170 180 MESDLHHIIR SDQPLTTEHI CYFMYQLLRG LKYIHSANVI HRDLKPSNLL VNENCELRIG 190 200 210 220 230 240 DFGMARAVSQ EPEDHKSFMT EYVATRWYRA PELMLSFGRY SQAIDMWSVG CIFAEMIGRR 250 260 270 280 290 300 QIFPGKHYVH QLQLIISVLG SPPSGLVSTI RSDRVRNYVT GLPSKSATPF KQLYTKATQP 310 320 330 340 350 360 MVDLLTSLLR FNPEERPTSV QALTHPFLSG YHDKDDEPTC HAPFDFQFEA TATREGVHEE 370 380 390 400 410 420 VTAVIKKYHE KKNRFAKQLT PIRRSEKTDP PKNDLLIFKK PAAPVSFPKE SAPDAASTMD 430 440 450 460 470 480 LDAGEAEAEK RPMITVQVLQ DEPVKDTKGA AKKKTISEDT KLKIRDIIFA SMFAKQKGLG 490 500 510 520 530 540 KPLDKVKKSV TAADRQKERE SKRKKRLDRA AEKERKRREE TKNLLSEADR SLLDRWTKMQ 550 560 570 580 590 600 KSTTTENPAK QTETEEPKVT LIRHQSLPPS SIRQARQRQL IEATNVRPNS VHIDDATWLV 610 620 630 640 650 660 PSLDARLAPE TPMLQPSTDH PTVAPNTSMV PNTSWGTNCT ENTQQKQVEV KRPSSLSVQP 670 680 690 700 710 720 SNQDLTNQTL TRSDTEGLTA ISPGTVDRVL TQQFHVNHDL HNPPQELEGA KQKEAARTPE 730 740 750 760 770 780 LAGRLNVSNH GEFPSLGAIG YGLGVDISDI IPQSAGDVAP GTSQELMTSA ASEQCSSSLL 790 800 810 AEWSDLHRMH PQDMEALQRE LELGSPMIVQ YET

References

[1]	"Genomewide surveys of developmentally relevant genes in Ciona intestinalis." Satou Y., Satoh N. Dev. Genes Evol. 213:211-212(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Genomewide surveys of developmentally relevant genes in Ciona intestinalis." Imai K.S., Hino K., Yagi K., Satoh N., Satou Y. Development 131:4047-4058(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Expressed genes in Ciona intestinalis." Satou Y. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB210409 mRNA. Translation: BAE06414.1.
RefSeq	NP_001071698.1. NM_001078230.1.
UniGene	Cin.30537.
3D structure databases
ProteinModelPortal	Q4H3L3.
SMR	Q4H3L3. Positions 31-350.
ModBase	Search...
Protein-protein interaction databases
STRING	7719.ENSCINP00000019973.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	778597.
KEGG	cin:778597.
Organism-specific databases
CTD	778597.
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000113595.
HOVERGEN	HBG108137.
InParanoid	Q4H3L3.
KO	K04464.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR003527. MAP_kinase_CS. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS01351. MAPK. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4H3L3_CIOIN

Accession

Primary (citable) accession number: Q4H3L3

Entry history

Integrated into UniProtKB/TrEMBL:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)