Q4H3G0 (Q4H3G0_CIOIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Frizzled receptor EMBL BAE06467.1

Gene names

Name:

Ci-Fz3/6 EMBL BAE06467.1

Organism

Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) EMBL BAE06467.1

Taxonomic identifier

7719 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona

Protein attributes

Sequence length	810 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 FZ (frizzled) domain. SAAS SAAS015526

Ontologies

Keywords
Biological process	Wnt signaling pathway SAAS SAAS015526
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS015526
Molecular function	Developmental protein SAAS SAAS015526 G-protein coupled receptor SAAS SAAS015526 Receptor Transducer
PTM	Disulfide bond SAAS SAAS015526
Gene Ontology (GO)
Biological_process	axonogenesis Inferred from Biological aspect of Ancestor. Source: RefGenome brain development Inferred from Biological aspect of Ancestor. Source: RefGenome canonical Wnt receptor signaling pathway Inferred from Biological aspect of Ancestor. Source: RefGenome embryo development Inferred from Biological aspect of Ancestor. Source: RefGenome gonad development Inferred from Biological aspect of Ancestor. Source: RefGenome vasculature development Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular_component	cell projection Inferred from Biological aspect of Ancestor. Source: RefGenome cytoplasm Inferred from Biological aspect of Ancestor. Source: RefGenome integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW PDZ domain binding Inferred from Biological aspect of Ancestor. Source: RefGenome Wnt-activated receptor activity Inferred from Biological aspect of Ancestor. Source: RefGenome Wnt-protein binding Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4H3G0 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: FABA3998C5258C1F	FASTA	810	89,818
	10 20 30 40 50 60 MDIKLGIIIL CCVISEVSTS NVHPQCRPVT LPMCLRNNNE RNKGIKWIYN ETTFPNFNND 70 80 90 100 110 120 ASESEVEISL SLLHPLLSTS CSRYLELFLC SVFSPACMGG GVVPPCRSLC EVVFHDCAEV 130 140 150 160 170 180 VEAFGIIWPQ RLHCDNFPPQ NGGKMVDTGS DTWGKMVVSR SSWLVWGEAL LGDGEVCIPL 190 200 210 220 230 240 SGDDVITPAL SQNNQEIDNV TKYPGEYGLR CPAQLTAPPN EPGYTFLGMQ GCGAPCPNMY 250 260 270 280 290 300 MGDDELMLVR YIICVLASLC ALVTSFVLFT FAIDTNRFRY PERPIVFYAA AYFVISVIFL 310 320 330 340 350 360 VGFALGSDVA CKHEIMDENN IVIQGAVVVE GPRDRACTIV FMILYFFTVN GTIWWLILTV 370 380 390 400 410 420 TWLLAAGFKW GSEAIEKHHL YYHGLAWGIP AVQTMVVVTT GKIEGDNIAG VCFVGLYDSD 430 440 450 460 470 480 GLRFLLLLPM SFYLLVGMFV LLTGFICLNR VRKSLHDDET NKKKLAKFML RIGVFSIMYI 490 500 510 520 530 540 LPQLALIAIY AIEDSNRKSW ESAWFVRNCG RYGVPCPNLP HPVAQLAQGN PLPGVFIFCM 550 560 570 580 590 600 KYIMTLIVAL PPLFWVASKK TMASWKEAVT KPRCMDDGNP LSVTQTQLLN DSNNGPHARD 610 620 630 640 650 660 AVRKQQSKHS DVIFGGLGGF QGSSASIAAA EAMTSSRARA RQELWEDMTS TDSTLSSRSE 670 680 690 700 710 720 STLAKVLEYE SHKNKGKRVV GRRRHNQGHP LPLTHNPDEG ENNREVDDVI NKPVPIKTER 730 740 750 760 770 780 NNRIDDVISS QSRSLSDVTR PQSSVTSQPG RPDVVKKQLS ISRSDATRSV PDIIKTTELS 790 800 810 PPLLRNKPEI PRKPKLSLAK SNTSGRVLEV

References

[1]	"Genomewide surveys of developmentally relevant genes in Ciona intestinalis." Satou Y., Satoh N. Dev. Genes Evol. 213:211-212(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Genomewide surveys of developmentally relevant genes in Ciona intestinalis." Imai K.S., Hino K., Yagi K., Satoh N., Satou Y. Development 131:4047-4058(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Expressed genes in Ciona intestinalis." Satou Y. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB210462 mRNA. Translation: BAE06467.1.
RefSeq	NP_001071723.1. NM_001078255.1.
UniGene	Cin.33254.
3D structure databases
ProteinModelPortal	Q4H3G0.
ModBase	Search...
Protein-protein interaction databases
STRING	7719.ENSCINP00000026933.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	778631.
KEGG	cin:778631.
Organism-specific databases
CTD	778631.
Phylogenomic databases
eggNOG	NOG262811.
HOGENOM	HOG000233237.
HOVERGEN	HBG074428.
InParanoid	Q4H3G0.
Family and domain databases
Gene3D	1.10.2000.10. 1 hit.
InterPro	IPR000539. Frizzled. IPR015526. Frizzled/SFRP. IPR020067. Frizzled_dom. IPR026543. FZD6. IPR017981. GPCR_2-like. [Graphical view]
PANTHER	PTHR11309. PTHR11309. 1 hit. PTHR11309:SF21. PTHR11309:SF21. 1 hit.
Pfam	PF01534. Frizzled. 1 hit. PF01392. Fz. 1 hit. [Graphical view]
PRINTS	PR00489. FRIZZLED.
SMART	SM00063. FRI. 1 hit. [Graphical view]
SUPFAM	SSF63501. Frizzled_Cys-rich. 1 hit.
PROSITE	PS50038. FZ. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4H3G0_CIOIN

Accession

Primary (citable) accession number: Q4H3G0

Entry history

Integrated into UniProtKB/TrEMBL:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)