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Protein

Mitogen-activated protein kinase

Gene

Ci-JNK

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:Ci-JNKImported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000018935.

Structurei

3D structure databases

ProteinModelPortaliQ4H3A2.
SMRiQ4H3A2. Positions 31-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
HOVERGENiHBG014652.
KOiK04440.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4H3A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQADEGMSN GKNKGANAPT GAATTGKDTA NTEFYTVQVS DSVFTVLKRY
60 70 80 90 100
QSLKPIGSGA QGMVCAAHDT VLGQHVAIKK LSRPFQNPTH AKRAYRELVL
110 120 130 140 150
MRAVNHKNII GLLNVFSPQS SYEDFSHVYL VMELMDASLC QVIQMDLDHE
160 170 180 190 200
RLSYLLYQLL CGIKHLHSAG IIHRDLKPSN IVVRSDCTLK ILDFGLARTA
210 220 230 240 250
GGSFMMTPYV VTRYYRAPEV ILGMGYQEVV DIWSVGCIFG EMIRGQVLFP
260 270 280 290 300
GNDHIDQWNK ITEQLGTPSE DFINKLQPTV RNYVLNRPFQ RGHPIHRLFP
310 320 330 340 350
DSLFPADSES NGRLRSSQAR DLLAKMLVVD PIGRITVDDA LQHPYIKIWY
360 370 380 390 400
DPSEVEGPGP KVDGGSIDEV DYSVEKWKEV IWTEVKLWDT VDTTVPNPVI
410 420 430
PLSTAVPDQP AEKLEPEKVE SNPDVPAATA QVVKAETEG
Length:439
Mass (Da):48,803
Last modified:August 30, 2005 - v1
Checksum:i5F7B4260A3A5BD18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB210520 mRNA. Translation: BAE06525.1.
RefSeqiNP_001071750.1. NM_001078282.1.
UniGeneiCin.22770.

Genome annotation databases

GeneIDi778660.
KEGGicin:778660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB210520 mRNA. Translation: BAE06525.1.
RefSeqiNP_001071750.1. NM_001078282.1.
UniGeneiCin.22770.

3D structure databases

ProteinModelPortaliQ4H3A2.
SMRiQ4H3A2. Positions 31-385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7719.ENSCINP00000018935.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi778660.
KEGGicin:778660.

Organism-specific databases

CTDi100533320.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
HOVERGENiHBG014652.
KOiK04440.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomewide surveys of developmentally relevant genes in Ciona intestinalis."
    Satou Y., Satoh N.
    Dev. Genes Evol. 213:211-212(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks."
    Imai K.S., Hino K., Yagi K., Satoh N., Satou Y.
    Development 131:4047-4058(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Expressed genes in Ciona intestinalis."
    Satou Y.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ4H3A2_CIOIN
AccessioniPrimary (citable) accession number: Q4H3A2
Entry historyi
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: June 24, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.