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Q4G1L2 (Q4G1L2_EPTBU) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:VLRB EMBL AAZ16361.1
OrganismEptatretus burgeri (Inshore hagfish) EMBL AAZ16361.1
Taxonomic identifier7764 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperotretiMyxiniformesMyxinidaeEptatretinaeEptatretus

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site1561Sulfate PDB 3UL7 PDB 3UL8 PDB 3UL9
Binding site1851Sulfate PDB 3UL7 PDB 3UL8 PDB 3UL9

Sequences

Sequence LengthMass (Da)Tools
Q4G1L2 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: 5B0BBBB883D12E2B

FASTA27330,001
        10         20         30         40         50         60 
MKFALRGTCV LLALLLCCRN GKACPSRCSC SGTEIRCNSK GLTSVPTGIP SSATRLELES 

        70         80         90        100        110        120 
NKLQSLPHGV FDKLTQLTKL SLSQNQIQSL PDGVFDKLTK LTILYLHENK LQSLPNGVFD 

       130        140        150        160        170        180 
KLTQLKELAL DTNQLKSVPD GIFDRLTSLQ KIWLHTNPWD CSCPRIDYLS RWLNKNSQKE 

       190        200        210        220        230        240 
QGSAKCSGSG KPVRSIICPT TTTTTTTTTM PTTTTLPTTT KMSMVKVPLV PPEAFGRVMN 

       250        260        270 
ACAYFPSYIF LHLVHGLAAV PLVYLICHAS QLL 

« Hide

References

[1]"Variable lymphocyte receptors in hagfish."
Pancer Z., Saha N.R., Kasamatsu J., Suzuki T., Amemiya C.T., Kasahara M., Cooper M.D.
Proc. Natl. Acad. Sci. U.S.A. 102:9224-9229(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Structural diversity of the hagfish variable lymphocyte receptors."
Kim H.M., Oh S.C., Lim K.J., Kasamatsu J., Heo J.Y., Park B.S., Lee H., Yoo O.J., Kasahara M., Lee J.O.
J. Biol. Chem. 282:6726-6732(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 24-200.
[3]"Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer."
Kang J.Y., Nan X., Jin M.S., Youn S.J., Ryu Y.H., Mah S., Han S.H., Lee H., Paik S.G., Lee J.O.
Immunity 31:873-884(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 133-200.
[4]"Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein."
Han J., Kim H.J., Lee S.C., Hong S., Park K., Jeon Y.H., Kim D., Cheong H.K., Kim H.S.
PLoS ONE 7:e30929-E30929(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.37 ANGSTROMS) OF 126-199 IN COMPLEX WITH SULFATE.
[5]"Structural basis of TLR5-flagellin recognition and signaling."
Yoon S.I., Kurnasov O., Natarajan V., Hong M., Gudkov A.V., Osterman A.L., Wilson I.A.
Science 335:859-864(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.47 ANGSTROMS) OF 126-200.
[6]"Liesegang-like patterns of Toll crystals grown in gel."
Gangloff M., Moreno A., Gay N.J.
J Appl Crystallogr 46:337-345(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 133-201.
[7]"Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation."
Lewis M., Arnot C.J., Beeston H., McCoy A., Ashcroft A.E., Gay N.J., Gangloff M.
Proc. Natl. Acad. Sci. U.S.A. 110:20461-20466(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 133-201.
[8]"Functional insights from the crystal structure of the N-terminal domain of the prototypical toll receptor."
Gangloff M., Arnot C.J., Lewis M., Gay N.J.
Structure 21:143-153(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) OF 133-201.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY965531 mRNA. Translation: AAZ16361.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2O6RX-ray2.30A24-200[»]
3A79X-ray2.90A133-200[»]
3A7BX-ray2.53A133-200[»]
3A7CX-ray2.40A133-200[»]
3UL7X-ray2.37A126-199[»]
3UL8X-ray2.50A126-199[»]
3UL9X-ray2.45A126-199[»]
3ULAX-ray3.60A/C126-199[»]
3V44X-ray2.83A126-200[»]
3V47X-ray2.47A/B126-200[»]
4ARNX-ray2.41A/B/C/D133-201[»]
4ARRX-ray3.00A/B133-201[»]
4BV4X-ray2.35R133-201[»]
ProteinModelPortalQ4G1L2.
SMRQ4G1L2. Positions 24-200.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG061418.

Family and domain databases

InterProIPR000483. Cys-rich_flank_reg_C.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRR-contain_N.
IPR024592. Variable_lymphocyte_rcpt_C.
[Graphical view]
PfamPF11921. DUF3439. 1 hit.
PF13855. LRR_8. 1 hit.
PF01462. LRRNT. 1 hit.
[Graphical view]
SMARTSM00369. LRR_TYP. 3 hits.
SM00082. LRRCT. 1 hit.
SM00013. LRRNT. 1 hit.
[Graphical view]
PROSITEPS51450. LRR. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ4G1L2.

Entry information

Entry nameQ4G1L2_EPTBU
AccessionPrimary (citable) accession number: Q4G1L2
Entry history
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)