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Protein
Submitted name:

Variable lymphocyte receptor B

Gene

VLRB

Organism
Eptatretus burgeri (Inshore hagfish)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei144Beta-D-mannose; via carbonyl oxygenIEA:1
Binding sitei146Mannose; via carbonyl oxygenIEA:1
Binding sitei153N-acetyl-D-glucosamineIEA:1
Binding sitei175FucoseIEA:1
Binding sitei185Beta-D-mannoseIEA:1

Keywordsi

Molecular functionReceptor0 Publication

Names & Taxonomyi

Protein namesi
Submitted name:
Variable lymphocyte receptor B0 Publication
Gene namesi
Name:VLRB0 Publication
OrganismiEptatretus burgeri (Inshore hagfish)0 Publication
Taxonomic identifieri7764 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperotretiMyxiniformesMyxinidaeEptatretinaeEptatretus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei248 – 267HelicalCuratedAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23CuratedAdd BLAST23
ChainiPRO_500423884324 – 273CuratedAdd BLAST250

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 30IEA:
Disulfide bondi28 ↔ 37IEA:
Disulfide bondi161 ↔ 186IEA:
Disulfide bondi163 ↔ 198IEA:

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2O6RX-ray2.30A24-200[»]
3A79X-ray2.90A133-200[»]
3A7BX-ray2.53A133-200[»]
3A7CX-ray2.40A133-200[»]
3UL7X-ray2.37A126-200[»]
3UL8X-ray2.50A126-199[»]
3UL9X-ray2.45A126-199[»]
3ULAX-ray3.60A/C126-199[»]
3V44X-ray2.83A126-200[»]
3V47X-ray2.47A/B126-200[»]
4ARNX-ray2.41A/B/C/D136-201[»]
4ARRX-ray3.00A/B136-201[»]
4BV4X-ray2.35R134-201[»]
4QDHX-ray2.40A/B126-200[»]
4QXEX-ray2.20A134-200[»]
4QXFX-ray2.25A/B129-200[»]
5GY2X-ray2.10A/B126-200[»]
5IJBX-ray2.91A/B126-200[»]
5IJCX-ray2.57A/B126-200[»]
5IJDX-ray2.70A/B126-200[»]
ProteinModelPortaliQ4G1L2.
SMRiQ4G1L2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ4G1L2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 55LRRNTImportedAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni176 – 179Mannose bindingIEA:4
Regioni190 – 191Beta-D-mannose bindingIEA:2

Keywords - Domaini

Leucine-rich repeatCurated, RepeatCurated, SignalCurated, Transmembrane, Transmembrane helixCurated

Phylogenomic databases

HOVERGENiHBG061418.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiView protein in InterPro
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR032675. LRR_dom_sf.
IPR000372. LRRNT.
IPR024592. Variable_lymphocyte_rcpt_C.
PfamiView protein in Pfam
PF11921. DUF3439. 1 hit.
PF13855. LRR_8. 1 hit.
PF01462. LRRNT. 1 hit.
SMARTiView protein in SMART
SM00369. LRR_TYP. 4 hits.
SM00013. LRRNT. 1 hit.
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiView protein in PROSITE
PS51450. LRR. 4 hits.

Sequencei

Sequence statusi: Complete.

Q4G1L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFALRGTCV LLALLLCCRN GKACPSRCSC SGTEIRCNSK GLTSVPTGIP
60 70 80 90 100
SSATRLELES NKLQSLPHGV FDKLTQLTKL SLSQNQIQSL PDGVFDKLTK
110 120 130 140 150
LTILYLHENK LQSLPNGVFD KLTQLKELAL DTNQLKSVPD GIFDRLTSLQ
160 170 180 190 200
KIWLHTNPWD CSCPRIDYLS RWLNKNSQKE QGSAKCSGSG KPVRSIICPT
210 220 230 240 250
TTTTTTTTTM PTTTTLPTTT KMSMVKVPLV PPEAFGRVMN ACAYFPSYIF
260 270
LHLVHGLAAV PLVYLICHAS QLL
Length:273
Mass (Da):30,001
Last modified:August 30, 2005 - v1
Checksum:i5B0BBBB883D12E2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY965531 mRNA. Translation: AAZ16361.1.

Similar proteinsi

Entry informationi

Entry nameiQ4G1L2_EPTBU
AccessioniPrimary (citable) accession number: Q4G1L2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: November 22, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureIEA: