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Protein

Carboxylic ester hydrolase

Gene

CES2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation

Enzyme and pathway databases

SABIO-RKiQ4G0E9.

Protein family/group databases

ESTHERihuman-CES2. Carb_B_Chordata.

Names & Taxonomyi

Protein namesi
Recommended name:
Carboxylic ester hydrolaseUniRule annotation (EC:3.1.1.-UniRule annotation)
Gene namesi
Name:CES2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ4G0E9.
PeptideAtlasiQ4G0E9.

Structurei

3D structure databases

ProteinModelPortaliQ4G0E9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 566COesteraseInterPro annotationAdd BLAST492

Sequence similaritiesi

Belongs to the type-B carboxylesterase/lipase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
HOGENOMiHOG000091866.
HOVERGENiHBG008839.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q4G0E9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PLTPCPVQTP RLGKALIHCW TDPGQPLGEQ QRVRRQRTET SEPTMRLHRL
60 70 80 90 100
RARLSAVACG LLLLLVRGQG QDSASPIRTT HTGQVLGSLV HVKGANAGVQ
110 120 130 140 150
TFLGIPFAKP PLGPLRFAPP EPPESWSGVR DGTTHPAMCL QDLTAVESEF
160 170 180 190 200
LSQFNMTFPS DSMSEDCLYL SIYTPAHSHE GSNLPVMVWI HGGALVFGMA
210 220 230 240 250
SLYDGSMLAA LENVVVVIIQ YRLGVLGFFS TGDKHATGNW GYLDQVAALR
260 270 280 290 300
WVQQNIAHFG GNPDRVTIFG ESAGGTSVSS LVVSPISQGL FHGAIMESGV
310 320 330 340 350
ALLPGLIASS ADVISTVVAN LSACDQVDSE ALVGCLRGKS KEEILAINKP
360 370 380 390 400
FKMIPGVVDG VFLPRHPQEL LASADFQPVP SIVGVNNNEF GWLIPKVMRI
410 420 430 440 450
YDTQKEMDRE ASQAALQKML TLLMLPPTFG DLLREEYIGD NGDPQTLQAQ
460 470 480 490 500
FQEMMADSMF VIPALQVAHF QCSRAPVYFY EFQHQPSWLK NIRPPHMKAD
510 520 530 540 550
HVKFTEEEEQ LSRKMMKYWA NFARNGNPNG EGLPHWPLFD QEEQYLQLNL
560 570 580
QPAVGRALKA HRLQFWKKAL PQKIQELEEP EERHTEL
Length:587
Mass (Da):64,920
Last modified:August 30, 2005 - v1
Checksum:i81FCB12A139A7580
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098417 mRNA. Translation: AAH98417.1.
UniGeneiHs.282975.

Similar proteinsi

Entry informationi

Entry nameiQ4G0E9_HUMAN
AccessioniPrimary (citable) accession number: Q4G0E9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: August 30, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.