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Protein
Submitted name:

BOP1 protein

Gene

BOP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesisSAAS annotation, rRNA processingSAAS annotation

Enzyme and pathway databases

SignaLinkiQ4G0D9.

Names & Taxonomyi

Protein namesi
Submitted name:
BOP1 proteinImported
Gene namesi
Name:BOP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleusnucleolus SAAS annotation
  • Nucleusnucleoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ4G0D9.
PRIDEiQ4G0D9.

Expressioni

Gene expression databases

BgeeiQ4G0D9.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000304151.

Structurei

3D structure databases

ProteinModelPortaliQ4G0D9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini230 – 27142WD_REPEATS_REGIONInterPro annotationAdd
BLAST
Domaini396 – 567172WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the WD repeat BOP1/ERB1 family.SAAS annotation

Keywords - Domaini

RepeatUniRule annotationSAAS annotation, WD repeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0650. Eukaryota.
ENOG410XRBX. LUCA.
HOVERGENiHBG008113.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
HAMAPiMF_03027. BOP1.
InterProiIPR028598. BOP1/Erb1.
IPR012953. BOP1_N_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08145. BOP1NT. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
SMARTiSM01035. BOP1NT. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q4G0D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DYWRTVQDPM TGRDLRLTDE QVALVRRLQS GQFGDVGFNP YEPAVDFFSG
60 70 80 90 100
DVMIHPVTNR PADKRSFIPS LVEKEKVSRM VHAIKMGWIQ PRRPRDPTPS
110 120 130 140 150
FYDLWAQEDP NAVLGRHKMH VPAPKLALPG HAESYNPPPE YLLSEEERLA
160 170 180 190 200
WEQQEPGERK LSFLPRKFPS LRAVPAYGRF IQERFERCLD LYLCPRQRKM
210 220 230 240 250
RVNVDPEDLI PKLPRPRDLQ PFPTCQALVY RGHSDLVRCL SVSPGGQWLV
260 270 280 290 300
SGSDDGSLRL WEVATARCVR TVPVGGVVKS VAWNPSPAVC LVAAAVEDSV
310 320 330 340 350
LLLNPALGDR LVAGSTDQLL SAFVPPEEPP LQPARWLEAS EEERQVGLRL
360 370 380 390 400
RICHGKPVTQ VTWHGRGDYL AVVLATQGHT QVLIHQLSRR RSQSPFRRSH
410 420 430 440 450
GQVQRVAFHP ARPFLLVASQ RSVRLYHLLR QELTKKLMPN CKWVSSLAVH
460 470 480 490 500
PAGDNVICGS YDSKLVWFDL DLSTKPYRML RHHKKALRAV AFHPRYPLFA
510 520 530 540 550
SGSDDGSVIV CHGMVYNDLL QNPLLVPVKV LKGHVLTRDL GVLDVIFHPT
560
QPWVFSSGAD GTVRLFT
Length:567
Mass (Da):64,081
Last modified:August 30, 2005 - v1
Checksum:i117B16F518DAFE0F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098446 mRNA. Translation: AAH98446.1.
UniGeneiHs.535901.
Hs.645279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098446 mRNA. Translation: AAH98446.1.
UniGeneiHs.535901.
Hs.645279.

3D structure databases

ProteinModelPortaliQ4G0D9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000304151.

Proteomic databases

PaxDbiQ4G0D9.
PRIDEiQ4G0D9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0650. Eukaryota.
ENOG410XRBX. LUCA.
HOVERGENiHBG008113.

Enzyme and pathway databases

SignaLinkiQ4G0D9.

Miscellaneous databases

ChiTaRSiBOP1. human.

Gene expression databases

BgeeiQ4G0D9.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
HAMAPiMF_03027. BOP1.
InterProiIPR028598. BOP1/Erb1.
IPR012953. BOP1_N_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF08145. BOP1NT. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
SMARTiSM01035. BOP1NT. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.

Entry informationi

Entry nameiQ4G0D9_HUMAN
AccessioniPrimary (citable) accession number: Q4G0D9
Entry historyi
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.