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Q4G075 (ILEUA_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Leukocyte elastase inhibitor A
Alternative name(s):
Serine protease inhibitor EIA
Serpin B1a
Gene names
Name:Serpinb1a
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Regulates the activity of the neutrophil proteases By similarity.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the serpin family. Ov-serpin subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 379379Leukocyte elastase inhibitor A
PRO_0000289123

Sites

Site344 – 3452Reactive bond By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4G075 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: 2335D7C019FF849C

FASTA37942,727
        10         20         30         40         50         60 
MEQLSSANSL FALELFHTLS ESSPTGNIFF SPFSISSALA MVFLGTKGTT AAQLSKTFHF 

        70         80         90        100        110        120 
DSVEDVHSRF QSLNAEVSKR GASHTLKLAN RLYGEKTYNF LPEFLTSTQK MYGADLAPVD 

       130        140        150        160        170        180 
FQHASEDARK EINQWVKGQT EGKIPELLAV GVVDSMTKLV LVNAIYFKGM WEEKFMKQDT 

       190        200        210        220        230        240 
TDAPFRLNKK NTKSVKMMYQ KKKFFFGYIS DLKCKVLEMP YQGGELSMVI LLPEDIEDES 

       250        260        270        280        290        300 
TGLKKIEEQI TLEKLREWTK RENLENIDVH VKLPRFKIEE SYILNSNLGR LGLQDLFNSS 

       310        320        330        340        350        360 
KADLSGMSGS RDLFISKIVH KAFVEVNEEG TEAAAATAGI ATFCMLLPEE EFTADHPFIF 

       370 
FIRHNPTANV LFLGRVCSP 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Thymus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC098686 mRNA. Translation: AAH98686.1.
RefSeqNP_001026812.1. NM_001031642.1.
UniGeneRn.103402.

3D structure databases

ProteinModelPortalQ4G075.
SMRQ4G075. Positions 1-327, 349-379.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000056600.

Proteomic databases

PaxDbQ4G075.
PRIDEQ4G075.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000059854; ENSRNOP00000056600; ENSRNOG00000016581.
GeneID291091.
KEGGrno:291091.
UCSCRGD:1306203. rat.

Organism-specific databases

CTD66222.
RGD1306203. Serpinb1a.

Phylogenomic databases

eggNOGCOG4826.
GeneTreeENSGT00740000115232.
HOGENOMHOG000238519.
HOVERGENHBG005957.
KOK13963.
OMATFHFNTV.
OrthoDBEOG7327PB.
PhylomeDBQ4G075.
TreeFamTF352619.

Gene expression databases

GenevestigatorQ4G075.

Family and domain databases

InterProIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. SSF56574. 1 hit.
PROSITEPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio632107.

Entry information

Entry nameILEUA_RAT
AccessionPrimary (citable) accession number: Q4G075
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families