Q4G034 (Q4G034_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dicer1 protein EMBL AAH98796.1

Gene names

Name:

Dicer1 RGD 1309381

Organism

Rattus norvegicus (Rat) EMBL AAH98796.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	401 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	negative regulation of Schwann cell proliferation Inferred from mutant phenotype PubMed 20648646. Source: BHF-UCL positive regulation of Schwann cell differentiation Inferred from mutant phenotype PubMed 20648646. Source: BHF-UCL positive regulation of myelination Inferred from mutant phenotype PubMed 20648646. Source: BHF-UCL production of miRNAs involved in gene silencing by miRNA Inferred from mutant phenotype PubMed 20648646. Source: BHF-UCL
Cellular_component	axon Inferred from direct assay PubMed 16723529. Source: RGD dendrite Inferred from direct assay PubMed 17888888. Source: RGD endoplasmic reticulum-Golgi intermediate compartment Inferred from direct assay PubMed 17888888. Source: RGD growth cone Inferred from direct assay PubMed 16723529. Source: RGD
Molecular_function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH98796.1

Sequences

	Sequence		Length	Mass (Da)
	Q4G034 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: F235C1BA99312141	FASTA	401	45,180
	10 20 30 40 50 60 EDDFVVGFWN PSEENCGVDT GKQSISYDLH TEQCIADKSI ADCVEALLGC YLTSCGERAA 70 80 90 100 110 120 QLFLCSLGLK VLPVIKRTSR DKASYPAQEN SSSQQKSPSG SCAAAVSPRS SAGKDLEYGC 130 140 150 160 170 180 LKIPPRCMFD HPDAEKTLNH LISGFENFEK KINYIFKNKA YLLQAFTHAS YHYNTITDCY 190 200 210 220 230 240 QRLEFLGDAI LDYLITKHLY EDPRQHSPGV LTDLRSALVN NTIFASLAVK YDYHKYFKAV 250 260 270 280 290 300 SPELFHVIDD FVQFQLEKNE MQGMDSELRR SEEDEEKEED IEVPKAMGDI FESLAGAIYM 310 320 330 340 350 360 DSGMSLEVVW QVYYPMMRPL IEKFSANVPR SPVRELLEME PETAKFSPAE RTYDGKVRVT 370 380 390 400 VELVGKGKFK GVGRSYRIAK SAAARRALRS LKANQPLVPN S

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Spleen EMBL AAH98796.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC098796 mRNA. Translation: AAH98796.1.
IPI	IPI00365891.
UniGene	Rn.205881.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000014405. Q4G034.
PTM databases
PhosphoSite	Q4G034.
Proteomic databases
PaxDb	Q4G034.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	RGD:1309381. rat.
Organism-specific databases
RGD	1309381. Dicer1.
Phylogenomic databases
eggNOG	COG1111.
HOGENOM	HOG000001567.
HOVERGEN	HBG092134.
InParanoid	Q4G034.
OrthoDB	EOG4JDH5W.
Gene expression databases
Genevestigator	Q4G034.
Family and domain databases
Gene3D	1.10.1520.10. 3 hits. 3.30.160.20. 1 hit.
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like_dom. IPR000999. RNase_III_dom. [Graphical view]
Pfam	PF00636. Ribonuclease_3. 2 hits. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4G034_RAT

Accession

Primary (citable) accession number: Q4G034

Entry history

Integrated into UniProtKB/TrEMBL:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	April 3, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)