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Q4FZX7 (SRPRB_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Signal recognition particle receptor subunit beta

Short name=SR-beta
Gene names
Name:Srprb
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR By similarity.

Subunit structure

Heterodimer with SRPR By similarity.

Subcellular location

Endoplasmic reticulum membrane; Single-pass membrane protein By similarity.

Sequence similarities

Belongs to the SRP receptor beta subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Signal recognition particle receptor subunit beta
PRO_0000331245

Regions

Transmembrane35 – 5521Helical; Potential
Nucleotide binding69 – 779GTP By similarity
Nucleotide binding90 – 934GTP By similarity

Sites

Binding site1181GTP; via amide nitrogen By similarity
Binding site2461GTP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4FZX7 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: DA63194232A47386

FASTA26929,569
        10         20         30         40         50         60 
MASANTRRVG DGAGGAFQPY LDSLRQELQQ RDPTLLSVAV AVLAVLLTLV FWKFIWSRKS 

        70         80         90        100        110        120 
SQRAVLFVGL CDSGKTLLFV RLLTGQYRDT QTSITDSSAI YKVNNNRGNS LTLIDLPGHE 

       130        140        150        160        170        180 
SLRLQFLDRF KSSARAVVFV VDSATFQREV KDVAEFLYQV LIDSMALKNT PAFLVACNKQ 

       190        200        210        220        230        240 
DIAMAKSAKL IQQQLEKELN TLRVTRSAAP STLDSSSTAP AQLGKKGKEF EFSQLPLKVE 

       250        260 
FLECSAKGGR GDAGSADVQD LEKWLAKIA 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC098951 mRNA. Translation: AAH98951.1.
RefSeqNP_001013270.1. NM_001013252.1.
UniGeneRn.138078.

3D structure databases

ProteinModelPortalQ4FZX7.
SMRQ4FZX7. Positions 63-269.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ4FZX7.
PRIDEQ4FZX7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID300965.
KEGGrno:300965.
UCSCRGD:1304698. rat.

Organism-specific databases

CTD58477.
RGD1304698. Srprb.

Phylogenomic databases

eggNOGCOG2229.
HOVERGENHBG054206.
InParanoidQ4FZX7.
KOK12272.

Gene expression databases

ArrayExpressQ4FZX7.
GenevestigatorQ4FZX7.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR027417. P-loop_NTPase.
IPR024156. Small_GTPase_ARF.
IPR019009. SRP_receptor_beta_su.
[Graphical view]
PfamPF09439. SRPRB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Other

NextBio647800.
PROQ4FZX7.

Entry information

Entry nameSRPRB_RAT
AccessionPrimary (citable) accession number: Q4FZX7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: August 30, 2005
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families