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Protein
Submitted name:

Serine incorporator 2

Gene

Serinc2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • phosphatidylserine metabolic process Source: HGNC
  • positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Source: BHF-UCL
  • positive regulation of serine C-palmitoyltransferase activity Source: BHF-UCL
  • sphingolipid metabolic process Source: HGNC

Enzyme and pathway databases

ReactomeiR-RNO-977347 Serine biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Serine incorporator 2Imported
Gene namesi
Name:Serinc2Imported
ORF Names:rCG_31282Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1311396 Serinc2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 57HelicalSequence analysisAdd BLAST22
Transmembranei100 – 121HelicalSequence analysisAdd BLAST22
Transmembranei133 – 151HelicalSequence analysisAdd BLAST19
Transmembranei158 – 179HelicalSequence analysisAdd BLAST22
Transmembranei199 – 226HelicalSequence analysisAdd BLAST28
Transmembranei238 – 256HelicalSequence analysisAdd BLAST19
Transmembranei268 – 286HelicalSequence analysisAdd BLAST19
Transmembranei315 – 337HelicalSequence analysisAdd BLAST23
Transmembranei381 – 399HelicalSequence analysisAdd BLAST19
Transmembranei420 – 444HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501430936220 – 450Sequence analysisAdd BLAST431

Expressioni

Gene expression databases

BgeeiENSRNOG00000012989

Interactioni

GO - Molecular functioni

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2592 Eukaryota
ENOG410XP7K LUCA
GeneTreeiENSGT00550000074522
HOGENOMiHOG000165463
HOVERGENiHBG025699
OMAiVWFYFGV
OrthoDBiEOG091G07WS

Family and domain databases

InterProiView protein in InterPro
IPR029554 SERINC2
IPR005016 TDE1/TMS
PANTHERiPTHR10383 PTHR10383, 1 hit
PTHR10383:SF22 PTHR10383:SF22, 1 hit
PfamiView protein in Pfam
PF03348 Serinc, 1 hit

Sequencei

Sequence statusi: Complete.

Q4FZV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGACLGACSL LSCASCLCGS APCILCSCCP STRNSTVSRL LFTGFLFLGV
60 70 80 90 100
LVSIIMLSPG VESQLYKLPW VCEDRAQQPV VLQGPLDCGS LLGFRAVYRM
110 120 130 140 150
CFATAAFFFL FMMLMICVRS SRDPRAAIQN GFWFFKFLIL VGITVGAFYI
160 170 180 190 200
PDGSFPKIWF YFGVVGSFLF ILIQLILFID FAHSWNQRWL CKAEECDSPV
210 220 230 240 250
WYAGLFFFTF LFYLLSIAAV ALMFVYYTES GACHEGKVFI GLNLTFCVCV
260 270 280 290 300
SIIAVLPKVQ SAQPNSGLLQ ASVVTLYTMF VTWSALSNVP DQKCNPHLPT
310 320 330 340 350
KNGTGQVNLE DYSTVWWDAP SIVGLVIFIL CTFFISLRSS DHRQVNSLMQ
360 370 380 390 400
TEECPAEMVQ QQQVAVGDGR TYDNEQDGVT YSYSFFHFCL VLASLHVMMT
410 420 430 440 450
LTNWYSPGET RKMISTWTSV WVKICASWAG LFLYLWTLVA PLLLPNRDFS
Length:450
Mass (Da):50,387
Last modified:August 30, 2005 - v1
Checksum:i66001E14CA5D48BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050017 Genomic DNA No translation available.
BC099093 mRNA Translation: AAH99093.1
DQ103709 mRNA Translation: AAZ80296.1
CH473968 Genomic DNA Translation: EDL80589.1
RefSeqiNP_001026826.1, NM_001031656.1
UniGeneiRn.144273

Genome annotation databases

EnsembliENSRNOT00000017577; ENSRNOP00000017577; ENSRNOG00000012989
GeneIDi313057
KEGGirno:313057
UCSCiRGD:1311396 rat

Similar proteinsi

Entry informationi

Entry nameiQ4FZV1_RAT
AccessioniPrimary (citable) accession number: Q4FZV1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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