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Protein
Submitted name:

Serine incorporator 2

Gene

Serinc2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • phosphatidylserine metabolic process Source: HGNC
  • positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Source: BHF-UCL
  • positive regulation of serine C-palmitoyltransferase activity Source: BHF-UCL
  • sphingolipid metabolic process Source: HGNC

Names & Taxonomyi

Protein namesi
Submitted name:
Serine incorporator 2Imported
Gene namesi
Name:Serinc2Imported
ORF Names:rCG_31282Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1311396. Serinc2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 57HelicalSequence analysisAdd BLAST22
Transmembranei100 – 121HelicalSequence analysisAdd BLAST22
Transmembranei133 – 151HelicalSequence analysisAdd BLAST19
Transmembranei158 – 179HelicalSequence analysisAdd BLAST22
Transmembranei199 – 226HelicalSequence analysisAdd BLAST28
Transmembranei238 – 256HelicalSequence analysisAdd BLAST19
Transmembranei268 – 286HelicalSequence analysisAdd BLAST19
Transmembranei315 – 337HelicalSequence analysisAdd BLAST23
Transmembranei381 – 399HelicalSequence analysisAdd BLAST19
Transmembranei420 – 444HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501084365620 – 450Sequence analysisAdd BLAST431

Expressioni

Gene expression databases

BgeeiENSRNOG00000012989.

Interactioni

GO - Molecular functioni

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2592. Eukaryota.
ENOG410XP7K. LUCA.
GeneTreeiENSGT00550000074522.
HOGENOMiHOG000165463.
HOVERGENiHBG025699.
OMAiVWFYFGV.
OrthoDBiEOG091G07WS.

Family and domain databases

InterProiView protein in InterPro
IPR029554. SERINC2.
IPR005016. TDE1/TMS.
PANTHERiPTHR10383. PTHR10383. 1 hit.
PTHR10383:SF31. PTHR10383:SF31. 1 hit.
PfamiView protein in Pfam
PF03348. Serinc. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4FZV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGACLGACSL LSCASCLCGS APCILCSCCP STRNSTVSRL LFTGFLFLGV
60 70 80 90 100
LVSIIMLSPG VESQLYKLPW VCEDRAQQPV VLQGPLDCGS LLGFRAVYRM
110 120 130 140 150
CFATAAFFFL FMMLMICVRS SRDPRAAIQN GFWFFKFLIL VGITVGAFYI
160 170 180 190 200
PDGSFPKIWF YFGVVGSFLF ILIQLILFID FAHSWNQRWL CKAEECDSPV
210 220 230 240 250
WYAGLFFFTF LFYLLSIAAV ALMFVYYTES GACHEGKVFI GLNLTFCVCV
260 270 280 290 300
SIIAVLPKVQ SAQPNSGLLQ ASVVTLYTMF VTWSALSNVP DQKCNPHLPT
310 320 330 340 350
KNGTGQVNLE DYSTVWWDAP SIVGLVIFIL CTFFISLRSS DHRQVNSLMQ
360 370 380 390 400
TEECPAEMVQ QQQVAVGDGR TYDNEQDGVT YSYSFFHFCL VLASLHVMMT
410 420 430 440 450
LTNWYSPGET RKMISTWTSV WVKICASWAG LFLYLWTLVA PLLLPNRDFS
Length:450
Mass (Da):50,387
Last modified:August 30, 2005 - v1
Checksum:i66001E14CA5D48BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050017 Genomic DNA. No translation available.
BC099093 mRNA. Translation: AAH99093.1.
DQ103709 mRNA. Translation: AAZ80296.1.
CH473968 Genomic DNA. Translation: EDL80589.1.
RefSeqiNP_001026826.1. NM_001031656.1.
UniGeneiRn.144273.

Genome annotation databases

EnsembliENSRNOT00000017577; ENSRNOP00000017577; ENSRNOG00000012989.
GeneIDi313057.
KEGGirno:313057.
UCSCiRGD:1311396. rat.

Similar proteinsi

Entry informationi

Entry nameiQ4FZV1_RAT
AccessioniPrimary (citable) accession number: Q4FZV1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: September 27, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported