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Q4FX34 (Q4FX34_LEIMA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=2.6.1.1 EMBL CAJ40954.1

Putative aspartate aminotransferase EMBL CBZ12710.1
EC=2.6.1.1 EMBL CBZ12710.1
Gene names
Name:asat EMBL CAJ40954.1
ORF Names:LMJF_35_0820 EMBL CBZ12710.1
OrganismLeishmania major [Reference proteome] EMBL CAJ40954.1
Taxonomic identifier5664 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequences

Sequence LengthMass (Da)Tools
Q4FX34 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: A6398BDDF00CB5BB

FASTA41245,990
        10         20         30         40         50         60 
MSTQAAMTTA ERWQKIQAQA PDVIFDLAKR AAAAKGPKAN LVIGAYRDEQ GRPYPLRVVR 

        70         80         90        100        110        120 
KAEQLLLDMN LDYEYLPISG YQPFIDEAVK IIYGNTVELE NLVAVQTLSG TGAVSLGAKL 

       130        140        150        160        170        180 
LTRVFDAETT PIYLSDPTWP NHYGVVKAAG WKNICTYAYY DPKTVSLNFE GMKKDILAAP 

       190        200        210        220        230        240 
DGSVFILHQC AHNPTGVDPS QEQWNEIASL MLAKHHQVFF DSAYQGYASG SLDTDAYAAR 

       250        260        270        280        290        300 
LFARRGIEVL LAQSFSKNMG LYSERAGTLS LLLKDKTKRA DVKSVMDSLI REEYTCPPAH 

       310        320        330        340        350        360 
GARLAHLILS NNELRKEWEA ELSAMAERIR TMRRTVYDEL LRLQTPGSWE HVINQIGMFS 

       370        380        390        400        410 
FLGLSKAQCE YCQNHNIFIT VSGRANMAGL THETALMLAQ TINDAVRNVN RE 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the kinetoplastid parasite, Leishmania major."
Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G. expand/collapse author list , Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B.G., Myler P.J.
Science 309:436-442(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Friedlin EMBL CBZ12710.1 and MHOM/IL/81/Friedlin.
[2]"Towards multilocus sequence typing of the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolic enzymes (ASAT, GPI, NH1, NH2, PGD)."
Mauricio I.L., Yeo M., Baghaei M., Doto D., Pratlong F., Zemanova E., Dedet J.P., Lukes J., Miles M.A.
Int. J. Parasitol. 36:757-769(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MHOM/SU/1973/5-ASKH EMBL CAJ40954.1.
[3]"Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania."
Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A., Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.
Genome Res. 21:2129-2142(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Friedlin EMBL CBZ12710.1.
[4]Aslett M.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Friedlin EMBL CBZ12710.1.
[5]"Chromosome and gene copy number variation allow genomic structural differences between species and strains of Leishmania."
Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K., Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Friedlin.
[6]"Crystal structure of a putative Aspartate Aminotransferase from Leishmania major Friedlin."
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Abendroth J., Edwards T.E., Staker B.L., Stewart L.J., Myler P.
Submitted (SEP-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM117189 Genomic DNA. Translation: CAJ40954.1.
FR796431 Genomic DNA. Translation: CBZ12710.1.
RefSeqXP_003722477.1. XM_003722429.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4H51X-ray1.85A/B1-412[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsLmjF.35.0820:mRNA; LmjF.35.0820:pep; LmjF.35.0820.
GeneID12982266.
KEGGlma:LMJF_35_0820.

Phylogenomic databases

HOGENOMHOG000185898.
KOK14454.
OMAMAGLTHE.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERPTHR11879. PTHR11879. 1 hit.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00799. TRANSAMINASE.
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ4FX34_LEIMA
AccessionPrimary (citable) accession number: Q4FX34
Secondary accession number(s): E9AEQ7, Q18L72
Entry history
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)