Reviewed, UniProtKB/Swiss-Prot Q4FVS6 (RLMF_PSYA2)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase F
    EC=2.1.1.48
Alternative name(s):
    23S rRNA mA1618 methyltransferase
    rRNA adenine N-6-methyltransferase

Gene names

Name:	rlmF
Ordered Locus Names:	Psyc_0008

Organism

Psychrobacter arcticus (strain DSM 17307 / 273-4) [Complete proteome] [HAMAP]

Taxonomic identifier

259536 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Psychrobacter

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the adenine in position 1618 of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine. HAMAP MF_01848
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. METT10D/rlmF family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA modification Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (adenine-N6-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848		PRO_0000349940

Sequences

	Sequence		Length	Mass (Da)
	Q4FVS6-1 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: 8811FDFCA999E536	FASTA	345	38,627
	10 20 30 40 50 60 MTSKPMTRRP TANNHRNRSP ETAKKLGQLH PRNPHQGRYD FVALTHALPE LAKHTITNPK 70 80 90 100 110 120 GEPTINFSDS AAVRVLNQAL LAHYYGVKFW DIPEGYLCPP IPGRADYIHY IADLLAQTTH 130 140 150 160 170 180 VNKDNTPPTG KEIHALDIGT GASAIYPIVG SQSYGWRFTA SDIDPISVNT AALICETNPK 190 200 210 220 230 240 LKSAVKVKLQ PEPKRIFANI IGRQDYFDVV VCNPPFHASL EEAMEANSRK QHNLQRHRGK 250 260 270 280 290 300 NENEQISRSS TKSGNAAQNL NFGGQHKELW SEGGEIAFLT KMAKESQDFA EHVGWFTTLV 310 320 330 340 SKSENVKPMQ LLLKQLGVAQ MRIIEMSQGQ KSTRILAWRF NTDEE

References

[1]

"Complete sequence of Psychrobacter arcticum 273-4." NASA Astrobiology Institute Ayala-del-Rio H.L., Chain P., Ponder M.A., Di Bartolo G., Ivanova N., Bergholz P.W., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J.A., Zarka D., Larimer F., Richardson P., Thomashow M.F., Tiedje J.M. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000082 Genomic DNA. Translation: AAZ17882.1.
RefSeq	YP_263316.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3514689.
GenomeReviews	Gene locus Psyc_0008 in contig CP000082_GR.
KEGG	par:Psyc_0008.
NMPDR	fig|259536.4.peg.509.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4FVS6.
OMA	Q4FVS6. LNFGGQN.
Family and domain databases
HAMAP	MF_01848. [Tree]
InterPro	IPR016909. S-AdoMet-dep_MeTrfase_YbiN_prd. IPR010286. SAM-Mtase_prd. [Graphical view]
PANTHER	PTHR13393. DUF890. 1 hit.
Pfam	PF05971. Methyltransf_10. 1 hit. [Graphical view]
PIRSF	PIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMF_PSYA2

Accession

Primary (citable) accession number: Q4FVS6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	August 30, 2005
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)