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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPARC259536:GI3A-8-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:Psyc_0008
OrganismiPsychrobacter arcticus (strain DSM 17307 / 273-4)
Taxonomic identifieri259536 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
Proteomesi
  • UP000000546 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 345345Ribosomal RNA large subunit methyltransferase FPRO_0000349940Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi259536.Psyc_0008.

Structurei

3D structure databases

ProteinModelPortaliQ4FVS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4FVS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSKPMTRRP TANNHRNRSP ETAKKLGQLH PRNPHQGRYD FVALTHALPE
60 70 80 90 100
LAKHTITNPK GEPTINFSDS AAVRVLNQAL LAHYYGVKFW DIPEGYLCPP
110 120 130 140 150
IPGRADYIHY IADLLAQTTH VNKDNTPPTG KEIHALDIGT GASAIYPIVG
160 170 180 190 200
SQSYGWRFTA SDIDPISVNT AALICETNPK LKSAVKVKLQ PEPKRIFANI
210 220 230 240 250
IGRQDYFDVV VCNPPFHASL EEAMEANSRK QHNLQRHRGK NENEQISRSS
260 270 280 290 300
TKSGNAAQNL NFGGQHKELW SEGGEIAFLT KMAKESQDFA EHVGWFTTLV
310 320 330 340
SKSENVKPMQ LLLKQLGVAQ MRIIEMSQGQ KSTRILAWRF NTDEE
Length:345
Mass (Da):38,627
Last modified:August 30, 2005 - v1
Checksum:i8811FDFCA999E536
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000082 Genomic DNA. Translation: AAZ17882.1.
RefSeqiWP_011279321.1. NC_007204.1.

Genome annotation databases

EnsemblBacteriaiAAZ17882; AAZ17882; Psyc_0008.
KEGGipar:Psyc_0008.
PATRICi23054125. VBIPsyArc98534_0009.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000082 Genomic DNA. Translation: AAZ17882.1.
RefSeqiWP_011279321.1. NC_007204.1.

3D structure databases

ProteinModelPortaliQ4FVS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi259536.Psyc_0008.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ17882; AAZ17882; Psyc_0008.
KEGGipar:Psyc_0008.
PATRICi23054125. VBIPsyArc98534_0009.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Enzyme and pathway databases

BioCyciPARC259536:GI3A-8-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
    Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
    Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17307 / 273-4.

Entry informationi

Entry nameiRLMF_PSYA2
AccessioniPrimary (citable) accession number: Q4FVS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: August 30, 2005
Last modified: November 11, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.