Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4FVL5

- IF2_PSYA2

UniProt

Q4FVL5 - IF2_PSYA2

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (30 Aug 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi418 – 4258GTPUniRule annotation
    Nucleotide bindingi464 – 4685GTPUniRule annotation
    Nucleotide bindingi518 – 5214GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPARC259536:GI3A-71-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:Psyc_0069
    OrganismiPsychrobacter arcticus (strain DSM 17307 / 273-4)
    Taxonomic identifieri259536 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
    ProteomesiUP000000546: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 908908Translation initiation factor IF-2PRO_0000228233Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi259536.Psyc_0069.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4FVL5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini409 – 578170tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni418 – 4258G1By similarity
    Regioni443 – 4475G2By similarity
    Regioni464 – 4674G3By similarity
    Regioni518 – 5214G4By similarity
    Regioni554 – 5563G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiHANTDVI.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q4FVL5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADKTVKELA DMVSKTASAV QQQLVDAGLP ARAEGDLVTE LEQEKLVTYL    50
    KQSHGQEEKR RISLKSKTTS TARVTGSSGK SKSVNVEVRK KKVFEKPDPE 100
    KMAEELAARE QAMIESQARA AKDAEDRAAT KKKSEERQAA TLAAMRASLG 150
    SSKKSDDKND DISTSVVVKK GGKTTIEVKP KEQPKKKVAA TKPKVETAVE 200
    RKAREVREKE EARLREIETE TRRTQAEEAQ KRTLEQMRKM AGQYTDQPAT 250
    EVRKDEPLAE GLVGDALEES FEKERREIKR GTSSTTARGR GRRKNQDERE 300
    IKNRKNGLRS SQSAQHKFEK PVEKIVYDVE ISEQITVSDL AQRMAVKARE 350
    VTKLLMKMGE IARESDTIDQ ATASLIVEEM GHNPVPVSDT KVEDDLQDAA 400
    DERSSNVQTR PPVVTIMGHV DHGKTSLLDK IRETKVATGE AGGITQHIGA 450
    YHVKTARGVI TFLDTPGHAA FSAMRSRGAQ ATDIVVLVVA ADDGMMPQTE 500
    EAIDHARAAG TPLIVAINKM DKPSADPDRV LNELTAKEVV SEEWGGDTPM 550
    ARISAKTGDG IDELLELISL QAELMELEAP LDGPAQGVVI ESRLEKGRGP 600
    VVSVLVKKGT LKQGDLVLAG EHYGKVRAMT DEHGQRIQSA GPSIPVEILG 650
    LPETPAAGSE FLVLTDEKKA REVADFRTNR ERERQLERQN AMRLESMFDQ 700
    MEQGNVSYLN IVLKTDVRGS LEALLSALNE LSTDEVKVRV ISSGVGPISE 750
    SDVTLAESSE AVLLGFNVRA DATARRKSDT ANMDIRYYSV IYGLIDDVKA 800
    AMSGMLAPEH REKILGVADV REVFRSSKFG AAAGCMVVEG TIYRNKPIRV 850
    LRNDQVIFTG QLQSLRRYKE DVNEVRTGME CGLAVRGYDV EAGDKIEVFE 900
    IQEFARTI 908
    Length:908
    Mass (Da):99,875
    Last modified:August 30, 2005 - v1
    Checksum:i7B5B55166A0CB41C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000082 Genomic DNA. Translation: AAZ17943.1.
    RefSeqiYP_263377.1. NC_007204.1.

    Genome annotation databases

    EnsemblBacteriaiAAZ17943; AAZ17943; Psyc_0069.
    GeneIDi3514157.
    KEGGipar:Psyc_0069.
    PATRICi23054275. VBIPsyArc98534_0082.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000082 Genomic DNA. Translation: AAZ17943.1 .
    RefSeqi YP_263377.1. NC_007204.1.

    3D structure databases

    ProteinModelPortali Q4FVL5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 259536.Psyc_0069.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ17943 ; AAZ17943 ; Psyc_0069 .
    GeneIDi 3514157.
    KEGGi par:Psyc_0069.
    PATRICi 23054275. VBIPsyArc98534_0082.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi HANTDVI.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci PARC259536:GI3A-71-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
      Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
      Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 17307 / 273-4.

    Entry informationi

    Entry nameiIF2_PSYA2
    AccessioniPrimary (citable) accession number: Q4FVL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 21, 2006
    Last sequence update: August 30, 2005
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3