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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei365 – 3651Proton donorUniRule annotation
Active sitei396 – 3961UniRule annotation
Active sitei522 – 5221UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPARC259536:GI3A-111-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Psyc_0109
OrganismiPsychrobacter arcticus (strain DSM 17307 / 273-4)
Taxonomic identifieri259536 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
ProteomesiUP000000546 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Glucose-6-phosphate isomerasePRO_0000180716Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi259536.Psyc_0109.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiISVMMAY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4FVH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDTKDNKVY SSARHSKYWQ QLQTLAESPW SLAALFAQDN TRTQHFSMQA
60 70 80 90 100
GALYMDYSKQ CIDDAVLENL LNLANSCELA ARIQSLLQGA MVNTSEERAA
110 120 130 140 150
LHTALRLPAT ASLQLDTQDV VADVHQSLLQ VERLSERVRS GTWRGFSGQA
160 170 180 190 200
ITDVVNIGVG GSDLGPLMAT TALDEWADTC VEVHFVSNMD GTQLDNLLKH
210 220 230 240 250
LNPETTLFII SSKSFGTVDT LSNAKTALSW LLATAKLRAG TEDSVRRRHF
260 270 280 290 300
IGISANGQKM SAWGIHPEHQ LQLWEWVGGR FSLWSAIGLA IAIRIGMSGF
310 320 330 340 350
KELLAGAHSM DDHFAQADFA KNVPVLLGLI AVWNSTFLQV NAHTVLPYDG
360 370 380 390 400
RLSYLPSYLT QLEMESNGKS VTQHGDRIDY DTCPILWGEI GSNAQHAFYQ
410 420 430 440 450
LLHQGTQQVS CDFIACVRRY SDEAKNTPLQ QQHELSLANC LAQSRVLAFG
460 470 480 490 500
NAAIAESDGQ VACDADKYKY YRGNQPSTTL LLDELTPHSL GALIALYEHK
510 520 530 540 550
VYVMASIWDI NPFDQWGVEM GKQMAESVHD AMQQERGAQF DTSTNQLLKH

IKELS
Length:555
Mass (Da):61,467
Last modified:August 30, 2005 - v1
Checksum:iD6D682DF0024C6B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000082 Genomic DNA. Translation: AAZ17983.1.
RefSeqiYP_263417.1. NC_007204.1.

Genome annotation databases

EnsemblBacteriaiAAZ17983; AAZ17983; Psyc_0109.
KEGGipar:Psyc_0109.
PATRICi23054365. VBIPsyArc98534_0127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000082 Genomic DNA. Translation: AAZ17983.1.
RefSeqiYP_263417.1. NC_007204.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi259536.Psyc_0109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ17983; AAZ17983; Psyc_0109.
KEGGipar:Psyc_0109.
PATRICi23054365. VBIPsyArc98534_0127.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiISVMMAY.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciPARC259536:GI3A-111-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
    Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
    Appl. Environ. Microbiol. 76:2304-2312(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17307 / 273-4.

Entry informationi

Entry nameiG6PI_PSYA2
AccessioniPrimary (citable) accession number: Q4FVH5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: August 30, 2005
Last modified: April 1, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.