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Q4FVH5 (G6PI_PSYA2) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Psyc_0109
OrganismPsychrobacter arcticus (strain DSM 17307 / 273-4) [Complete proteome] [HAMAP]
Taxonomic identifier259536 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 555555Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180716

Sites

Active site3651Proton donor By similarity
Active site3961 By similarity
Active site5221 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4FVH5 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: D6D682DF0024C6B3

FASTA55561,467
        10         20         30         40         50         60 
MNDTKDNKVY SSARHSKYWQ QLQTLAESPW SLAALFAQDN TRTQHFSMQA GALYMDYSKQ 

        70         80         90        100        110        120 
CIDDAVLENL LNLANSCELA ARIQSLLQGA MVNTSEERAA LHTALRLPAT ASLQLDTQDV 

       130        140        150        160        170        180 
VADVHQSLLQ VERLSERVRS GTWRGFSGQA ITDVVNIGVG GSDLGPLMAT TALDEWADTC 

       190        200        210        220        230        240 
VEVHFVSNMD GTQLDNLLKH LNPETTLFII SSKSFGTVDT LSNAKTALSW LLATAKLRAG 

       250        260        270        280        290        300 
TEDSVRRRHF IGISANGQKM SAWGIHPEHQ LQLWEWVGGR FSLWSAIGLA IAIRIGMSGF 

       310        320        330        340        350        360 
KELLAGAHSM DDHFAQADFA KNVPVLLGLI AVWNSTFLQV NAHTVLPYDG RLSYLPSYLT 

       370        380        390        400        410        420 
QLEMESNGKS VTQHGDRIDY DTCPILWGEI GSNAQHAFYQ LLHQGTQQVS CDFIACVRRY 

       430        440        450        460        470        480 
SDEAKNTPLQ QQHELSLANC LAQSRVLAFG NAAIAESDGQ VACDADKYKY YRGNQPSTTL 

       490        500        510        520        530        540 
LLDELTPHSL GALIALYEHK VYVMASIWDI NPFDQWGVEM GKQMAESVHD AMQQERGAQF 

       550 
DTSTNQLLKH IKELS 

« Hide

References

[1]"The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17307 / 273-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000082 Genomic DNA. Translation: AAZ17983.1.
RefSeqYP_263417.1. NC_007204.1.

3D structure databases

ProteinModelPortalQ4FVH5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING259536.Psyc_0109.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ17983; AAZ17983; Psyc_0109.
GeneID3514479.
KEGGpar:Psyc_0109.
PATRIC23054365. VBIPsyArc98534_0127.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMAPICVDGT.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycPARC259536:GI3A-111-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PSYA2
AccessionPrimary (citable) accession number: Q4FVH5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: August 30, 2005
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways