Reviewed, UniProtKB/Swiss-Prot Q4FUZ9 (UBIC_PSYA2)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Psyc_0289

Organism

Psychrobacter arcticus (strain DSM 17307 / 273-4) [Complete proteome] [HAMAP]

Taxonomic identifier

259536 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Psychrobacter

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 168	168	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240564
Sites
	Binding site	75	1	Substrate By similarity
	Binding site	114	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4FUZ9-1 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: 8D4D57DEBA524609	FASTA	168	19,277
	10 20 30 40 50 60 MTSHLCCSNY SSPLPELLVC LHTEGSLTAL LEVKAGQPLR VERSFEGYRL LSLAQKKQLG 70 80 90 100 110 120 MQGAALSRPR LAWVREVQLY GNDELPWVQA QSLFPLSSLQ GSARRLQQLK STPIGYVLFK 130 140 150 160 RSRTLPNQRF IKHTVDGWQR QTLYNWYGRP LLISETFLPQ FCEKQLDI

References

[1]

"Complete sequence of Psychrobacter arcticum 273-4." NASA Astrobiology Institute Ayala-del-Rio H.L., Chain P., Ponder M.A., Di Bartolo G., Ivanova N., Bergholz P.W., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J.A., Zarka D., Larimer F., Richardson P., Thomashow M.F., Tiedje J.M. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000082 Genomic DNA. Translation: AAZ18159.1.
RefSeq	YP_263593.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q4FUZ9.
Genome annotation databases
GeneID	3514183.
GenomeReviews	Gene locus Psyc_0289 in contig CP000082_GR.
KEGG	par:Psyc_0289.
NMPDR	fig|259536.4.peg.459.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3161.
HOGENOM	HBG289129.
OMA	ISETFLP.
Enzyme and pathway databases
BioCyc	PARC259536:PSYC_0289-MONOMER.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_PSYA2

Accession

Primary (citable) accession number: Q4FUZ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	August 30, 2005
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)