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Q4FUD6 (Q4FUD6_PSYA2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Protein translocase subunit SecY HAMAP-Rule MF_01465
Gene names
Name:secY HAMAP-Rule MF_01465 EMBL AAZ18372.1
Ordered Locus Names:Psyc_0509 EMBL AAZ18372.1
OrganismPsychrobacter arcticus (strain DSM 17307 / 273-4) [Complete proteome] [HAMAP] EMBL AAZ18372.1
Taxonomic identifier259536 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Psychrobacter ›

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently By similarity. HAMAP-Rule MF_01465

Subunit structure

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA By similarity. HAMAP-Rule MF_01465

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01465.

Sequence similarities

Belongs to the SecY/SEC61-alpha family. RuleBase RU004349 HAMAP-Rule MF_01465

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane25 – 4521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane80 – 10021Helical; By similarity HAMAP-Rule MF_01465
Transmembrane125 – 14521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane151 – 17121Helical; By similarity HAMAP-Rule MF_01465
Transmembrane180 – 20021Helical; By similarity HAMAP-Rule MF_01465
Transmembrane214 – 23421Helical; By similarity HAMAP-Rule MF_01465
Transmembrane269 – 28921Helical; By similarity HAMAP-Rule MF_01465
Transmembrane319 – 33921Helical; By similarity HAMAP-Rule MF_01465
Transmembrane375 – 39521Helical; By similarity HAMAP-Rule MF_01465
Transmembrane399 – 41921Helical; By similarity HAMAP-Rule MF_01465

Sequences

Sequence LengthMass (Da)Tools
Q4FUD6 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: E031AB5D4B1E9F67

FASTA44348,653
        10         20         30         40         50         60 
MSSTGIPLNP FAFIRKYDEL WTRLLFLIGA LIVYRLGSHI PVPGINPVNL ADLFSRNENT 

        70         80         90        100        110        120 
ILSMFNLFSG GALERMSIMA LGIMPYISAS IIVQMMSAVL PSLEALKKEG EAGRRKLNKY 

       130        140        150        160        170        180 
TRQGTLALAL VQSLGMCAGL ISQNLTLSSG LTFYIPAVTS LVAGAMFLMW LGEQITERGV 

       190        200        210        220        230        240 
GNGISMLIFA SIVAGTPGMI SQSIEQVNQG QMNLIVLFIF ALLGVAVTAG IVYIERAQRR 

       250        260        270        280        290        300 
VPVNYAQKQQ QGRKIYAQQQ SHLPLKLNMA GVIPAIFASS LLLFPASLGQ WVGQSTDPTL 

       310        320        330        340        350        360 
TQKILQNMAL VLSPGQPLYL VLFGAMIIFF CYFYTALVFS PREVAENLKR SGAYIPGIRP 

       370        380        390        400        410        420 
GQQTQRYLDH VLNRLTFIGA MYMTVICLMP MVVQSSFGVP FQLGGTSLLI MVVVVMDFIS 

       430        440 
QIQAHLMTHQ YHDQTLIQSP TQL

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References

[1]"The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17307 / 273-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000082 Genomic DNA. Translation: AAZ18372.1.
RefSeqYP_263806.1. NC_007204.1.

3D structure databases

ProteinModelPortalQ4FUD6.
ModBaseSearch...

Protein-protein interaction databases

STRING259536.Psyc_0509.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ18372; AAZ18372; Psyc_0509.
GeneID3514308.
KEGGpar:Psyc_0509.
PATRIC23055375. VBIPsyArc98534_0618.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0201.
HOGENOMHOG000080585.
KOK03076.
OMAFIMWLGE.
ProtClustDBPRK09204.

Enzyme and pathway databases

BioCycPARC259536:GI3A-589-MONOMER.

Family and domain databases

Gene3D1.10.3370.10. 1 hit.
HAMAPMF_01465. SecY.
InterProIPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERPTHR10906. PTHR10906. 1 hit.
PfamPF00344. SecY. 1 hit.
[Graphical view]
PIRSFPIRSF004557. SecY. 1 hit.
SUPFAMSSF103491. SecY. 1 hit.
TIGRFAMsTIGR00967. 3a0501s007. 1 hit.
PROSITEPS00755. SECY_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4FUD6_PSYA2
AccessionPrimary (citable) accession number: Q4FUD6
Entry history
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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